Hemophagocytic lymphohistiocytosis and visceral leishmaniasis in children: case report and systematic review of literature

Antonio Ruggiero, Stefano Mastrangelo, Palma Maurizi, Maria Scalzone, Giovanna Trombatore, Vita Ridola, Riccardo Riccardi

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

10 Citazioni (Scopus)

Abstract

emophagocytic lymphohistiocytosis is a potentially fatal disorder resulting from excessive activation and non-malignant proliferation of T lymphocytes and macrophages. Neoplasms, autoimmune disorders and systemic infections can cause secondary hemophagocytic syndrome. The association of hemophagocytic syndrome and visceral leishmaniasis is rarely found in childhood. We report a case of an infant affected by hemophagocytic lymphohistiocytosis secondary to visceral leishamniasis and describe all cases of hemophagocytic syndrome associated with visceral leishamniasis in childhood reported in literature, focusing on clinical manifestation, diagnosis and treatment.
Lingua originaleEnglish
pagine (da-a)103-108
Numero di pagine6
RivistaJournal of Infection in Developing Countries
Volume10
DOI
Stato di pubblicazionePubblicato - 2016

Keywords

  • Amphotericin B
  • Antiprotozoal Agents
  • Humans
  • Infant
  • Leishmaniasis, Visceral
  • Lymphohistiocytosis, Hemophagocytic
  • Male

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