Hemangioma of the umbilical cord with associated amnionic inclusion cyst: two uncommon entities occurring simultaneously

Umbilical cord hemangioma is an uncommon benign vascular neoplasm arising from the free segment of the umbilical cord, distinct from placental\r\nand fetal insertion, and is thought to originate from endothelial cells of the umbilical vessels. Cystic changes in the umbilical cord rarely\r\noccur as a consequence of the damage to the amnionic surface of the cord caused by the presence of the hemangioma. Until now, a total of 8\r\ncases of umbilical cord hemangioma associated with cystic changes in the umbilical cord have been reported in the literature, however, among\r\nthese cases, only one showed an associated cyst derived from inclusion of the amniotic epithelium, and the remaining seven cases consisted\r\nof hemangiomas with associated pseudocyst of the umbilical cord. We herein report a case of umbilical cord hemangioma with an associated\r\namnionic epithelial inclusion cyst. Clinicopathological features and differential diagnostic considerations are also discussed.