Health-related quality of life in epilepsy: findings obtained with a new Italian instrument

Salvatore Mazza, A Piazzini, Ettore Beghi, K Turner, M Ferraroni

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

27 Citazioni (Scopus)


The aim of the present study was to evaluate the Epi-QoL, a new Italian-specific measure of health-related quality of life (HRQOL) for adults with epilepsy; the clinical variables that affected the HRQOL score were also assessed. The Epi-QoL is a 46-item self-administered questionnaire focusing on six domains: Physical Functioning, Cognitive Functioning, Emotional Well-Being, Social Functioning, Seizure Worry, and Medication Effects. Eight hundred fifteen patients recruited from 24 secondary and tertiary Italian centers for the care of epilepsy were assessed. The results supported the reliability and validity of the Epi-QoL as a measure of HRQOL. The variables that significantly affected HRQOL scores were: geographic area, gender, seizure frequency, prognostic categories, number of medications, comorbidity, presence of cognitive impairment, psychiatric disturbances, and disability. We believe that a new specific questionnaire for the evaluation of HRQOL in Italy can contribute much to the understanding of the influence of epilepsy on patients' lives.
Lingua originaleEnglish
pagine (da-a)119-126
Numero di pagine8
Stato di pubblicazionePubblicato - 2008
Pubblicato esternamente


  • Adult
  • Epilepsy
  • Female
  • Health Status
  • Health Status Indicators
  • Humans
  • Italy
  • Male
  • Middle Aged
  • Quality of Life
  • Questionnaires
  • Severity of Illness Index


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