Gut Microbiome in Retina Health: The Crucial Role of the Gut-Retina Axis

Gianluca Scuderi*, Emidio Troiani, Angelo Maria Minnella

*Autore corrispondente per questo lavoro

Risultato della ricerca: Contributo in rivistaArticolo in rivista


The term microbiome means not only a complex ecosystem of microbial species that colonize our body but also their genome and the surrounding environment in which they live. Recent studies support the existence of a gut-retina axis involved in the pathogenesis of several chronic progressive ocular diseases, including age-related macular disorders. This review aims to underline the importance of the gut microbiome in relation to ocular health. After briefly introducing the characteristics of the gut microbiome in terms of composition and functions, the role of gut microbiome dysbiosis, in the development or progression of retinal diseases, is highlighted, focusing on the relationship between gut microbiome composition and retinal health based on the recently investigated gut-retina axis.
Lingua originaleEnglish
pagine (da-a)1-11
Numero di pagine11
RivistaFrontiers in Microbiology
Stato di pubblicazionePubblicato - 2022


  • age-related macular degeneration
  • gut-retina axis
  • leaky-gut
  • microbiome
  • microbiota
  • micronutrient
  • personalized medicine


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