GSTM1-null polymorphism as possible risk marker for hypertension: results from the aging and longevity study in the Sirente Geographic Area (ilSIRENTE study)

Graziano Onder, Concetta Santonocito, Roberto Bernabei, Ettore Domenico Capoluongo, Paola Concolino, Andrea Russo, Cecilia Zuppi, Francesco Luigi Landi, F Ameglio

Risultato della ricerca: Contributo in rivistaArticolo in rivista

27 Citazioni (Scopus)

Abstract

Involvement of various gene mutations in hypertension have been already reported, including GST (detoxification Phase II enzymes), with contrasting results. This study analyzes a possible association between GSTM1-null and GSTT1-null polymorphisms and the hypertension status in a very old population (>80 years).
Lingua originaleEnglish
pagine (da-a)92-96
Numero di pagine5
RivistaClinica chimica acta; international journal of clinical chemistry
Volume399
DOI
Stato di pubblicazionePubblicato - 2009

Keywords

  • Aged, 80 and over
  • Aging
  • Base Sequence
  • Female
  • Genetic Markers
  • Genetic Predisposition to Disease
  • Genotype
  • Geography
  • Glutathione Transferase
  • Humans
  • Hypertension
  • Italy
  • Longevity
  • Male
  • Polymorphism, Genetic
  • Regression Analysis

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