GSTM1-null polymorphism as possible risk marker for hypertension: results from the aging and longevity study in the Sirente Geographic Area (ilSIRENTE study)

Ettore Domenico Capoluongo; Graziano Onder; Paola Concolino; Andrea Russo; Concetta Santonocito; Roberto Bernabei; Cecilia Zuppi; F Ameglio; Francesco Luigi Landi

doi:10.1016/j.cca.2008.09.017

GSTM1-null polymorphism as possible risk marker for hypertension: results from the aging and longevity study in the Sirente Geographic Area (ilSIRENTE study)

Ettore Domenico Capoluongo, Graziano Onder, Paola Concolino, Andrea Russo, Concetta Santonocito, Roberto Bernabei, Cecilia Zuppi, F Ameglio, Francesco Luigi Landi

Risultato della ricerca: Contributo in rivista › Articolo in rivista

27 Citazioni (Scopus)

Abstract

Involvement of various gene mutations in hypertension have been already reported, including GST (detoxification Phase II enzymes), with contrasting results. This study analyzes a possible association between GSTM1-null and GSTT1-null polymorphisms and the hypertension status in a very old population (>80 years).

Lingua originale	English
pagine (da-a)	92-96
Numero di pagine	5
Rivista	Clinica chimica acta; international journal of clinical chemistry
Volume	399
DOI	https://doi.org/10.1016/j.cca.2008.09.017
Stato di pubblicazione	Pubblicato - 2009

Keywords

Aged, 80 and over
Aging
Base Sequence
Female
Genetic Markers
Genetic Predisposition to Disease
Genotype
Geography
Glutathione Transferase
Humans
Hypertension
Italy
Longevity
Male
Polymorphism, Genetic
Regression Analysis

Accesso al documento

10.1016/j.cca.2008.09.017

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Capoluongo, E. D., Onder, G., Concolino, P., Russo, A., Santonocito, C., Bernabei, R., Zuppi, C., Ameglio, F., & Landi, F. L. (2009). GSTM1-null polymorphism as possible risk marker for hypertension: results from the aging and longevity study in the Sirente Geographic Area (ilSIRENTE study). Clinica chimica acta; international journal of clinical chemistry, 399, 92-96. https://doi.org/10.1016/j.cca.2008.09.017

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title = "GSTM1-null polymorphism as possible risk marker for hypertension: results from the aging and longevity study in the Sirente Geographic Area (ilSIRENTE study)",

abstract = "Involvement of various gene mutations in hypertension have been already reported, including GST (detoxification Phase II enzymes), with contrasting results. This study analyzes a possible association between GSTM1-null and GSTT1-null polymorphisms and the hypertension status in a very old population (>80 years).",

keywords = "Aged, 80 and over, Aging, Base Sequence, Female, Genetic Markers, Genetic Predisposition to Disease, Genotype, Geography, Glutathione Transferase, Humans, Hypertension, Italy, Longevity, Male, Polymorphism, Genetic, Regression Analysis, Aged, 80 and over, Aging, Base Sequence, Female, Genetic Markers, Genetic Predisposition to Disease, Genotype, Geography, Glutathione Transferase, Humans, Hypertension, Italy, Longevity, Male, Polymorphism, Genetic, Regression Analysis",

author = "Capoluongo, {Ettore Domenico} and Graziano Onder and Paola Concolino and Andrea Russo and Concetta Santonocito and Roberto Bernabei and Cecilia Zuppi and F Ameglio and Landi, {Francesco Luigi}",

year = "2009",

doi = "10.1016/j.cca.2008.09.017",

language = "English",

volume = "399",

pages = "92--96",

journal = "Clinica chimica acta; international journal of clinical chemistry",

}

Capoluongo, ED, Onder, G, Concolino, P, Russo, A, Santonocito, C, Bernabei, R, Zuppi, C, Ameglio, F & Landi, FL 2009, 'GSTM1-null polymorphism as possible risk marker for hypertension: results from the aging and longevity study in the Sirente Geographic Area (ilSIRENTE study)', Clinica chimica acta; international journal of clinical chemistry, vol. 399, pagg. 92-96. https://doi.org/10.1016/j.cca.2008.09.017

GSTM1-null polymorphism as possible risk marker for hypertension: results from the aging and longevity study in the Sirente Geographic Area (ilSIRENTE study). / Capoluongo, Ettore Domenico; Onder, Graziano; Concolino, Paola et al.
In: Clinica chimica acta; international journal of clinical chemistry, Vol. 399, 2009, pag. 92-96.

Risultato della ricerca: Contributo in rivista › Articolo in rivista

TY - JOUR

T1 - GSTM1-null polymorphism as possible risk marker for hypertension: results from the aging and longevity study in the Sirente Geographic Area (ilSIRENTE study)

AU - Capoluongo, Ettore Domenico

AU - Onder, Graziano

AU - Concolino, Paola

AU - Russo, Andrea

AU - Santonocito, Concetta

AU - Bernabei, Roberto

AU - Zuppi, Cecilia

AU - Ameglio, F

AU - Landi, Francesco Luigi

PY - 2009

Y1 - 2009

N2 - Involvement of various gene mutations in hypertension have been already reported, including GST (detoxification Phase II enzymes), with contrasting results. This study analyzes a possible association between GSTM1-null and GSTT1-null polymorphisms and the hypertension status in a very old population (>80 years).

AB - Involvement of various gene mutations in hypertension have been already reported, including GST (detoxification Phase II enzymes), with contrasting results. This study analyzes a possible association between GSTM1-null and GSTT1-null polymorphisms and the hypertension status in a very old population (>80 years).

KW - Aged, 80 and over

KW - Aging

KW - Base Sequence

KW - Female

KW - Genetic Markers

KW - Genetic Predisposition to Disease

KW - Genotype

KW - Geography

KW - Glutathione Transferase

KW - Humans

KW - Hypertension

KW - Italy

KW - Longevity

KW - Male

KW - Polymorphism, Genetic

KW - Regression Analysis

KW - Aged, 80 and over

KW - Aging

KW - Base Sequence

KW - Female

KW - Genetic Markers

KW - Genetic Predisposition to Disease

KW - Genotype

KW - Geography

KW - Glutathione Transferase

KW - Humans

KW - Hypertension

KW - Italy

KW - Longevity

KW - Male

KW - Polymorphism, Genetic

KW - Regression Analysis

UR - http://hdl.handle.net/10807/33847

U2 - 10.1016/j.cca.2008.09.017

DO - 10.1016/j.cca.2008.09.017

M3 - Article

VL - 399

SP - 92

EP - 96

JO - Clinica chimica acta; international journal of clinical chemistry

JF - Clinica chimica acta; international journal of clinical chemistry

ER -

GSTM1-null polymorphism as possible risk marker for hypertension: results from the aging and longevity study in the Sirente Geographic Area (ilSIRENTE study)

Abstract

Keywords

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