Glucokinase regulatory protein gene polymorphism affects liver fibrosis in non-alcoholic fatty liver disease

Stefania Boccia, Antonio Grieco, Salvatore Petta, Elisabetta Bugianesi, Calogero Cammà, Chiara Rosso, Daniela Cabibi, Vito Di Marco, Stefania Grimaudo, Rosaria Maria Pipitone, Giulio Marchesini, Antonio Craxì

Risultato della ricerca: Contributo in rivistaArticolo in rivista

79 Citazioni (Scopus)

Abstract

Variant in glucokinase regulatory protein (GCKR), associated with lipid and glucose traits, has been suggested to affect fatty liver infiltration. We aimed to assess whether GCKR rs780094 C→T SNP influences the expression of steatosis, lobular inflammation and fibrosis in NAFLD patients, after correction for PNPLA3 genotype.
Lingua originaleEnglish
pagine (da-a)e87523-e87523
RivistaPLoS One
Volume9
DOI
Stato di pubblicazionePubblicato - 2014

Keywords

  • GENETICS
  • GLUCKINASE
  • LIVER FIBROSIS
  • NAFLD

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