Glioblastoma in multiple sclerosis: a case report

Giovanni Frisullo, Agata Katia Patanella, Viviana Nociti, Raffaele Iorio, Assunta Bianco, Alessandro Marti, Anna Paola Batocchi, Alessandro Cianfoni, Pietro Attilio Tonali

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

8 Citazioni (Scopus)

Abstract

Cerebral tumor and multiple sclerosis (MS) relapses can show overlapping clinical and magnetic resonance imaging features. In a previous study we observed in relapsing MS patients increased T-bet, pSTAT1, and pSTAT3 expressions in circulating mononuclear cells. During the data analysis we observed that T-bet, pSTAT1, and pSTAT3 expression was not increased in circulating mononuclear cells from a relapsing-remitting (RR)MS patient with recent onset of new neurological signs due to glioblastoma multiforme. In conclusion, our patient represents an exemplary case which suggests that T-bet, pSTAT1, and pSTAT3 expression in peripheral blood mononuclear cells (PBMCs) might be useful to differentiate MS relapses from other noninflammatory diseases.
Lingua originaleEnglish
pagine (da-a)141-144
Numero di pagine4
RivistaJournal of Neuro-Oncology
Stato di pubblicazionePubblicato - 2009

Keywords

  • glioblastoma multiforme
  • multiple sclerosis

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