Genome-wide expression profiling of the response to short-term exposure to fluconazole in Cryptococcus neoformans serotype A

Giovanni Fadda, Maurizio Sanguinetti, Brunella Posteraro, Elena De Carolis, Riccardo Torelli, Selene Ferrari, Dominique Sanglard

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

28 Citazioni (Scopus)

Abstract

Fluconazole (FLC), a triazole antifungal drug, is widely used for the maintenance therapy of cryptococcal meningoencephalitis, the most common opportunistic infection in AIDS patients. In this study, we examined changes in the gene expression profile of the C. neoformans reference strain H99 (serotype A) following FLC treatment in order to investigate the adaptive cellular responses to drug stress.
Lingua originaleEnglish
pagine (da-a)97-97
Numero di pagine13
RivistaBMC Microbiology
Volume11
DOI
Stato di pubblicazionePubblicato - 2011

Keywords

  • Antifungal Agents
  • Cryptococcus neoformans
  • Fluconazole
  • Gene Expression Profiling
  • Gene Expression Regulation, Fungal
  • Humans
  • Stress, Physiological

Fingerprint

Entra nei temi di ricerca di 'Genome-wide expression profiling of the response to short-term exposure to fluconazole in Cryptococcus neoformans serotype A'. Insieme formano una fingerprint unica.

Cita questo