Abstract
Bone marrow- and adipose tissue-derived mesenchymal stromal cells (MSC) represent promising sources for regenerative medicine. However, the precise molecular mechanisms underlying MSC stemness maintenance versus differentiation are not fully understood. The aim of this study was to compare the genome-wide expression profiles of bone marrow-and adipose tissue-derived MSC, in order to identify a common molecular stemness core.
| Lingua originale | Inglese |
|---|---|
| pagine (da-a) | 329-340 |
| Numero di pagine | 12 |
| Rivista | Cytotherapy |
| Volume | 13 |
| DOI | |
| Stato di pubblicazione | Pubblicato - 2011 |
Keywords
- Adipose Tissue
- Adult
- Binding Sites
- Bone Marrow Cells
- Cell Differentiation
- Cell Lineage
- Chromatin Immunoprecipitation
- Female
- Gene Expression Profiling
- Gene Expression Regulation
- Gene Knockdown Techniques
- Humans
- Kruppel-Like Transcription Factors
- Male
- Mesenchymal Stem Cells
- Middle Aged
- Models, Biological
- Polymerase Chain Reaction
- Promoter Regions, Genetic
- Protein Binding
- Reproducibility of Results
- Stromal Cells
- Young Adult
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