Gastric adenocarcinoma presenting as thrombotic microangiopathy in a 14-year-old girl

Palma Maurizi, Antonio Ruggiero, Daniela Rizzo, Annalisa Arlotta, Giorgio Attina', Riccardo Riccardi

Risultato della ricerca: Contributo in rivistaArticolo in rivista

2 Citazioni (Scopus)

Abstract

Gastric adenocarcinoma is rare in childhood and often presents with disseminated malignancy at diagnosis due to aspecific symptoms leading to delay in diagnosis. A familial predisposition for gastrointestinal cancer is suggested for the development of this early-onset adenocarcinoma. We report the case of a 14-year-old girl with a familial history of colorectal, liver, and breast cancers affected by metastatic gastric adenocarcinoma, who first presented with thrombotic microangiopathy. Thrombotic microangiopathy as first clinical presentation of metastatic gastric cancer is an exceptional event in childhood and represents a challenge for pediatricians. Gastric adenocarcinoma should be suspected in young patients with a significant familial history and also in the absence of initial specific signs, so as to provide correct diagnosis and appropriate treatment. Copyright © 2011 by Lippincott Williams & Wilkins.
Lingua originaleEnglish
pagine (da-a)e213-e215
Numero di pagine3
RivistaJOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
Volume33
DOI
Stato di pubblicazionePubblicato - 2011

Keywords

  • C reactive protein
  • abdominal pain
  • thrombotic microangiopathy

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