GABAB Agonists for the Treatment of Alcohol Use Disorder

Antonio Mirijello; Francesco Maria Caputo; Gabriele Angelo Vassallo; Antonio Gasbarrini; Giovanni Addolorato

GABAB Agonists for the Treatment of Alcohol Use Disorder

Antonio Mirijello, Francesco Maria Caputo, Gabriele Angelo Vassallo, Antonio Gasbarrini, Giovanni Addolorato

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Abstract

Almost 10% of the world's population is affected by alcohol use disorder (AUD). The combination between psychosocial intervention and pharmacological treatment seems to be the most effective approach for patients affected by AUD. Among effective drugs useful in the treatment of AUD, GABAB-ergic medications have been tested with encouraging results (i.e. sodium oxybate, baclofen, gabapentin, pregabalin and tiagabine). The present review will summarize available data on these medications.

Lingua originale	English
pagine (da-a)	3367-3372
Numero di pagine	6
Rivista	Current Pharmaceutical Design
Volume	21
Stato di pubblicazione	Pubblicato - 2015

Keywords

alcohol use disorder
gabab

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abstract = "Almost 10% of the world's population is affected by alcohol use disorder (AUD). The combination between psychosocial intervention and pharmacological treatment seems to be the most effective approach for patients affected by AUD. Among effective drugs useful in the treatment of AUD, GABAB-ergic medications have been tested with encouraging results (i.e. sodium oxybate, baclofen, gabapentin, pregabalin and tiagabine). The present review will summarize available data on these medications.",

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T1 - GABAB Agonists for the Treatment of Alcohol Use Disorder

AU - Mirijello, Antonio

AU - Caputo, Francesco Maria

AU - Vassallo, Gabriele Angelo

AU - Gasbarrini, Antonio

AU - Addolorato, Giovanni

PY - 2015

Y1 - 2015

N2 - Almost 10% of the world's population is affected by alcohol use disorder (AUD). The combination between psychosocial intervention and pharmacological treatment seems to be the most effective approach for patients affected by AUD. Among effective drugs useful in the treatment of AUD, GABAB-ergic medications have been tested with encouraging results (i.e. sodium oxybate, baclofen, gabapentin, pregabalin and tiagabine). The present review will summarize available data on these medications.

AB - Almost 10% of the world's population is affected by alcohol use disorder (AUD). The combination between psychosocial intervention and pharmacological treatment seems to be the most effective approach for patients affected by AUD. Among effective drugs useful in the treatment of AUD, GABAB-ergic medications have been tested with encouraging results (i.e. sodium oxybate, baclofen, gabapentin, pregabalin and tiagabine). The present review will summarize available data on these medications.

KW - alcohol use disorder

KW - gabab

KW - alcohol use disorder

KW - gabab

UR - http://hdl.handle.net/10807/68223

M3 - Article

VL - 21

SP - 3367

EP - 3372

JO - Current Pharmaceutical Design

JF - Current Pharmaceutical Design

SN - 1381-6128

ER -

GABAB Agonists for the Treatment of Alcohol Use Disorder

Abstract

Keywords

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