TY - JOUR
T1 - Functional and structural correlates of persistent ST elevation after acute myocardial infarction successfully treated by percutaneous coronary intervention
AU - Galiuto, Leonarda
AU - Barchetta, Sabrina
AU - Paladini, Serena
AU - Lanza, Gaetano Antonio
AU - Rebuzzi, Antonio Giuseppe
AU - Marzilli, Mario
AU - Crea, Filippo
PY - 2007
Y1 - 2007
N2 - Background: In the thrombolytic era, persistence of ST-segment elevation was considered a marker of LV aneurysm. ST-segment elevation may still be found persistently elevated after successful primary PCI. Echocardiographic correlates of this finding, however, are still poorly known.
Methods and Results: Eighty-two consecutive patients with first STEMI and successful PCI were divided in patients with persistent ST- segment elevation at discharge (sum of ST > 4 mm) (n=33) and without persistent ST- segment elevation (n=49). Conventional and myocardial contrast echocardiography (MCE) were performed at discharge and at 6 months. At discharge, LV aneurysm was more frequent in persistent ST-elevation patients (30%, p<0.005). Similarly, WMSI was higher (p<0.005) and microvascular damage larger (p<0.005) in patients with persistent ST-segment elevation. At 6 months follow-up, LV volumes were similar in the two groups.
Conclusions: After primary PCI, persistent ST-segment elevation is associated with LV aneurysm formation in 30% of cases, it is not associated with significantly larger LV dilation but with larger microvascular damage and dysfunctioning risk area
AB - Background: In the thrombolytic era, persistence of ST-segment elevation was considered a marker of LV aneurysm. ST-segment elevation may still be found persistently elevated after successful primary PCI. Echocardiographic correlates of this finding, however, are still poorly known.
Methods and Results: Eighty-two consecutive patients with first STEMI and successful PCI were divided in patients with persistent ST- segment elevation at discharge (sum of ST > 4 mm) (n=33) and without persistent ST- segment elevation (n=49). Conventional and myocardial contrast echocardiography (MCE) were performed at discharge and at 6 months. At discharge, LV aneurysm was more frequent in persistent ST-elevation patients (30%, p<0.005). Similarly, WMSI was higher (p<0.005) and microvascular damage larger (p<0.005) in patients with persistent ST-segment elevation. At 6 months follow-up, LV volumes were similar in the two groups.
Conclusions: After primary PCI, persistent ST-segment elevation is associated with LV aneurysm formation in 30% of cases, it is not associated with significantly larger LV dilation but with larger microvascular damage and dysfunctioning risk area
KW - AMI
KW - ST elevation
KW - AMI
KW - ST elevation
UR - http://hdl.handle.net/10807/32919
M3 - Article
SN - 1355-6037
SP - 1376
EP - 1380
JO - Heart
JF - Heart
ER -