Functional and morphologic findings at four years after intravitreal bevacizumab or laser for type 1 ROP

Domenico Lepore, Eugenio Maria Mercuri, Giulia Maria Amorelli, Daniela Ricci, Marco H. Ji, Graham E. Quinn, Lorenzo Orazi

Risultato della ricerca: Contributo in rivistaArticolo in rivista

1 Citazioni (Scopus)

Abstract

BACKGROUND AND OBJECTIVE: To compare morphologic and functional status at age 4 years for patients treated in one eye with laser photocoagulation and the other eye with intravitreal bevacizumab (IVB) injection for Type 1 retinopathy of prematurity (ROP). PATIENTS AND METHODS: In this single-center, randomized, controlled trial, best-corrected visual acuity (BCVA) in logMAR was obtained along with spherical equivalent refraction (SER), fluorescein angiography (FA), optical coherent tomography (OCT), and OCT angiography (OCTA). RESULTS: Eighteen babies (36 eyes) were selected for this study. BCVA and SER were similar in the two groups, but six patients had anisometropia of 4 diopters or more. IVB-treated eyes tended to have thinner foveal thickness than laser-treated eyes (mean difference: –5.33 pixels; 95% confidence interval, –9.62 to –1.05). CONCLUSION: Although the differences found here are minimal between the IVB-treated and laser-treated groups, further long-term evaluation of not only FA, but also OCT and OCTA, are needed in larger studies.
Lingua originaleEnglish
pagine (da-a)180-186
Numero di pagine7
RivistaOPHTHALMIC SURGERY, LASERS & IMAGING
Volume51
DOI
Stato di pubblicazionePubblicato - 2020

Keywords

  • Retinopathy of Prematurity

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