From bone marrow to the arterial wall: the ongoing tale of endothelial progenitor cells

Filippo Crea, Antonio Maria Leone, Maria Benedetta Giannico, Vincenzo Zaccone, Domenico D'Amario, Antonio Giuseppe Rebuzzi, Massimo Valgimigli, Matteo Perfetti

Risultato della ricerca: Contributo in rivistaArticolo in rivista

131 Citazioni (Scopus)

Abstract

Several physiological and pathophysiological stimuli or drugs modulate endothelial progenitor cell (EPC) mobilization. Moreover, levels of circulating EPCs predict cardiovascular risk and left ventricular remodelling after myocardial infarction. Nevertheless, our understanding in this field is complicated by lack of an unequivocal definition of EPCs, thus limiting their clinical applications. This review summarizes current knowledge and uncertainties on EPC characterization and mobilization in the attempt to define their role in the management of cardiovascular diseases.
Lingua originaleEnglish
pagine (da-a)890-899
Numero di pagine10
RivistaEuropean Heart Journal
DOI
Stato di pubblicazionePubblicato - 2009

Keywords

  • endothelial progenitor cell

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