Frailty in Elderly Patients with Covid-19: A Narrative Review

Sara Salini*, Andrea Russo, Giuseppe De Matteis, Andrea Piccioni, Davide Della Polla, Luigi Carbone, Christian Barillaro, Francesco Landi, Francesco Franceschi, Marcello Covino

*Autore corrispondente per questo lavoro

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review


Introduction: The SARS CoV-2 pandemic still generates a very high number of affected patients and a significant mortality rate. It is essential to establish objective criteria to stratify COVID-19 death risk. Frailty has been identified as a potential determinant of increased vulnerability in older adults affected by COVID-19, because it may suggest alterations of physical performance and functional autonomy. Methods: We have conducted a narrative review of the literature on the evidences regarding COVID-19 and the frailty condition. Thirteen observational studies were included. Conclusion: Data emerging from the studies indicate that older COVID-19 patients with a frailty condition have an increased risk of mortality compared with non-frail patients, and this association is independent of other clinical and demographic factors. A frailty evaluation is required to help clinicians to better stratify the overall risk of death for older patients with COVID-19.
Lingua originaleEnglish
pagine (da-a)1-7
Numero di pagine7
RivistaGerontology and Geriatric Medicine
Stato di pubblicazionePubblicato - 2022


  • COVID-
  • COVID-19
  • frailty
  • multi-morbidity
  • older adults


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