TY - JOUR
T1 - Fractional Flow Reserve–Based Coronary Artery Bypass Surgery: Current Evidence and Future Directions
AU - Spadaccio, Cristiano
AU - Glineur, David
AU - Barbato, Emanuele
AU - Di Franco, Antonino
AU - Oldroyd, Keith G.
AU - Biondi-Zoccai, Giuseppe
AU - Crea, Filippo
AU - Fremes, Stephen E.
AU - Angiolillo, Dominick J.
AU - Gaudino, Mario Fulvio Luigi
PY - 2020
Y1 - 2020
N2 - Fractional flow reserve (FFR) provides an objective measurement of the severity of ischemia caused by coronary stenoses in downstream myocardial regions. Data from the interventional cardiology realm have suggested benefits of a FFR-guided percutaneous coronary intervention (PCI) strategy. Limited evidence is available on the use of FFR to guide coronary artery bypass grafting (CABG). The most recent data have shown that FFR might simplify CABG procedures and optimize patency of arterial grafts without any clear impact on clinical outcomes. The aim of this review was to summarize the available data on FFR-based CABG and discuss the rationale and potential consequences of a switch toward FFR-based surgical revascularization strategy.
AB - Fractional flow reserve (FFR) provides an objective measurement of the severity of ischemia caused by coronary stenoses in downstream myocardial regions. Data from the interventional cardiology realm have suggested benefits of a FFR-guided percutaneous coronary intervention (PCI) strategy. Limited evidence is available on the use of FFR to guide coronary artery bypass grafting (CABG). The most recent data have shown that FFR might simplify CABG procedures and optimize patency of arterial grafts without any clear impact on clinical outcomes. The aim of this review was to summarize the available data on FFR-based CABG and discuss the rationale and potential consequences of a switch toward FFR-based surgical revascularization strategy.
KW - CABG
KW - Cardiac Catheterization
KW - Coronary Angiography
KW - Coronary Artery Bypass
KW - Coronary Artery Disease
KW - FFR
KW - Fractional Flow Reserve, Myocardial
KW - Humans
KW - Predictive Value of Tests
KW - Treatment Outcome
KW - Vascular Patency
KW - myocardial revascularization
KW - CABG
KW - Cardiac Catheterization
KW - Coronary Angiography
KW - Coronary Artery Bypass
KW - Coronary Artery Disease
KW - FFR
KW - Fractional Flow Reserve, Myocardial
KW - Humans
KW - Predictive Value of Tests
KW - Treatment Outcome
KW - Vascular Patency
KW - myocardial revascularization
UR - http://hdl.handle.net/10807/166835
U2 - 10.1016/j.jcin.2019.12.017
DO - 10.1016/j.jcin.2019.12.017
M3 - Article
SN - 1936-8798
VL - 13
SP - 1086
EP - 1096
JO - JACC: Cardiovascular Interventions
JF - JACC: Cardiovascular Interventions
ER -