Food protein-induced enterocolitis syndrome, from practice to theory

Stefano Miceli Sopo, Monica Greco, Serena Monaco, Salvatore Tripodi, Mauro Calvani

Risultato della ricerca: Contributo in rivistaArticolo in rivista

41 Citazioni (Scopus)


Food protein-induced enterocolitis syndrome (FPIES) is an allergic disease, probably non-IgE-mediated, with expression predominantly in the GI tract. The most characteristic symptom is repeated, debilitating vomiting. It occurs 2-6 h after ingestion of culprit food and is usually accompanied by pallor and lethargy. There may be diarrhea, and in 10-20% of cases, severe hypotension. These symptoms resolve completely within a few hours. The food most frequently involved is cow's milk, followed by rice, but many other foods may be involved. The prognosis is generally good in a few years. In this review the authors try to cope, with the help of some case histories, with the practical clinical aspects of FPIES. The authors also try to provide a management approach based on current knowledge, and finally, to point out the aspects of FPIES that are still controversial.
Lingua originaleEnglish
pagine (da-a)707-715
Numero di pagine9
RivistaExpert Review of Clinical Immunology
Stato di pubblicazionePubblicato - 2013


  • Age of Onset
  • Animals
  • Cattle
  • Cortisone
  • Diet Therapy
  • Enterocolitis
  • Female
  • Food
  • Food Hypersensitivity
  • Humans
  • Hypotension
  • Infant
  • Male
  • Syndrome
  • Vomiting


Entra nei temi di ricerca di 'Food protein-induced enterocolitis syndrome, from practice to theory'. Insieme formano una fingerprint unica.

Cita questo