Follicular thyroid neoplasms can be classified as low- and high-risk according to HBME-1 and Galectin-3 expression on liquid-based fine-needle cytology

Guido Fadda; Ed Rossi; Marco Raffaelli; Alfredo Pontecorvi; Stefano Sioletic; Francesca Morassi; Celestino Pio Lombardi; Gf Zannoni; Guido Rindi

doi:10.1530/EJE-11-0181

Follicular thyroid neoplasms can be classified as low- and high-risk according to HBME-1 and Galectin-3 expression on liquid-based fine-needle cytology

Guido Fadda, Ed Rossi, Marco Raffaelli, Alfredo Pontecorvi, Stefano Sioletic, Francesca Morassi, Celestino Pio Lombardi, Gf Zannoni, Guido Rindi

Risultato della ricerca: Contributo in rivista › Articolo in rivista

Abstract

Fine-needle aspiration biopsy (FNAB) is the most reliable diagnostic tool in the diagnosis of thyroid nodules. A cytologic diagnosis of follicular neoplasm with atypical cells of undetermined significance (FN/AUS) implies that the selection of patients between surgery and follow-up is difficult. In this setting immunocytochemical stainings might be helpful. The efficacy of a panel made up of HBME-1 and Galectin-3 antibodies is evaluated in cases processed by liquid-based cytology (LBC).

Lingua originale	English
pagine (da-a)	447-453
Numero di pagine	7
Rivista	European Journal of Endocrinology
Volume	165
DOI	https://doi.org/10.1530/EJE-11-0181
Stato di pubblicazione	Pubblicato - 2011

Keywords

Adolescent
Adult
Aged
Biopsy, Fine-Needle
Cytodiagnosis
Female
Galectin 3
Humans
Immunohistochemistry
Male
Middle Aged
Risk Assessment
Thyroid Neoplasms
Thyroid Nodule
Tumor Markers, Biological

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title = "Follicular thyroid neoplasms can be classified as low- and high-risk according to HBME-1 and Galectin-3 expression on liquid-based fine-needle cytology",

abstract = "Fine-needle aspiration biopsy (FNAB) is the most reliable diagnostic tool in the diagnosis of thyroid nodules. A cytologic diagnosis of follicular neoplasm with atypical cells of undetermined significance (FN/AUS) implies that the selection of patients between surgery and follow-up is difficult. In this setting immunocytochemical stainings might be helpful. The efficacy of a panel made up of HBME-1 and Galectin-3 antibodies is evaluated in cases processed by liquid-based cytology (LBC).",

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author = "Guido Fadda and Ed Rossi and Marco Raffaelli and Alfredo Pontecorvi and Stefano Sioletic and Francesca Morassi and Lombardi, {Celestino Pio} and Gf Zannoni and Guido Rindi",

year = "2011",

doi = "10.1530/EJE-11-0181",

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T1 - Follicular thyroid neoplasms can be classified as low- and high-risk according to HBME-1 and Galectin-3 expression on liquid-based fine-needle cytology

AU - Fadda, Guido

AU - Rossi, Ed

AU - Raffaelli, Marco

AU - Pontecorvi, Alfredo

AU - Sioletic, Stefano

AU - Morassi, Francesca

AU - Lombardi, Celestino Pio

AU - Zannoni, Gf

AU - Rindi, Guido

PY - 2011

Y1 - 2011

N2 - Fine-needle aspiration biopsy (FNAB) is the most reliable diagnostic tool in the diagnosis of thyroid nodules. A cytologic diagnosis of follicular neoplasm with atypical cells of undetermined significance (FN/AUS) implies that the selection of patients between surgery and follow-up is difficult. In this setting immunocytochemical stainings might be helpful. The efficacy of a panel made up of HBME-1 and Galectin-3 antibodies is evaluated in cases processed by liquid-based cytology (LBC).

AB - Fine-needle aspiration biopsy (FNAB) is the most reliable diagnostic tool in the diagnosis of thyroid nodules. A cytologic diagnosis of follicular neoplasm with atypical cells of undetermined significance (FN/AUS) implies that the selection of patients between surgery and follow-up is difficult. In this setting immunocytochemical stainings might be helpful. The efficacy of a panel made up of HBME-1 and Galectin-3 antibodies is evaluated in cases processed by liquid-based cytology (LBC).

KW - Adolescent

KW - Adult

KW - Aged

KW - Biopsy, Fine-Needle

KW - Cytodiagnosis

KW - Female

KW - Galectin 3

KW - Humans

KW - Immunohistochemistry

KW - Male

KW - Middle Aged

KW - Risk Assessment

KW - Thyroid Neoplasms

KW - Thyroid Nodule

KW - Tumor Markers, Biological

KW - Adolescent

KW - Adult

KW - Aged

KW - Biopsy, Fine-Needle

KW - Cytodiagnosis

KW - Female

KW - Galectin 3

KW - Humans

KW - Immunohistochemistry

KW - Male

KW - Middle Aged

KW - Risk Assessment

KW - Thyroid Neoplasms

KW - Thyroid Nodule

KW - Tumor Markers, Biological

UR - http://hdl.handle.net/10807/2658

U2 - 10.1530/EJE-11-0181

DO - 10.1530/EJE-11-0181

M3 - Article

VL - 165

SP - 447

EP - 453

JO - European Journal of Endocrinology

JF - European Journal of Endocrinology

SN - 0804-4643

ER -

Follicular thyroid neoplasms can be classified as low- and high-risk according to HBME-1 and Galectin-3 expression on liquid-based fine-needle cytology

Abstract

Keywords

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