Follicular thyroid neoplasms can be classified as low- and high-risk according to HBME-1 and Galectin-3 expression on liquid-based fine-needle cytology

Marco Raffaelli, Alfredo Pontecorvi, Celestino Pio Lombardi, Guido Rindi, Guido Fadda, Stefano Sioletic, Francesca Morassi, Ed Rossi, Gf Zannoni

Risultato della ricerca: Contributo in rivistaArticolo in rivista

Abstract

Fine-needle aspiration biopsy (FNAB) is the most reliable diagnostic tool in the diagnosis of thyroid nodules. A cytologic diagnosis of follicular neoplasm with atypical cells of undetermined significance (FN/AUS) implies that the selection of patients between surgery and follow-up is difficult. In this setting immunocytochemical stainings might be helpful. The efficacy of a panel made up of HBME-1 and Galectin-3 antibodies is evaluated in cases processed by liquid-based cytology (LBC).
Lingua originaleEnglish
pagine (da-a)447-453
Numero di pagine7
RivistaEuropean Journal of Endocrinology
Volume165
DOI
Stato di pubblicazionePubblicato - 2011

Keywords

  • Adolescent
  • Adult
  • Aged
  • Biopsy, Fine-Needle
  • Cytodiagnosis
  • Female
  • Galectin 3
  • Humans
  • Immunohistochemistry
  • Male
  • Middle Aged
  • Risk Assessment
  • Thyroid Neoplasms
  • Thyroid Nodule
  • Tumor Markers, Biological

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