Fertility preservation in patients with BRCA mutations or Lynch syndrome

Giovanni Scambia, Anna Fagotti, Giacomo Corrado, Rita Trozzi

Risultato della ricerca: Contributo in rivistaArticolo in rivista

1 Citazioni (Scopus)

Abstract

Guidelines and expert consensus are lacking on fertility preservation in BRCA mutation carriers and in patients with Lynch syndrome. The safety of fertility preservation in this setting is still a topic of debate and multiple factors need to be carefully considered. The aim of this review was to analyze the reproductive potential of women harboring a genetic mutation affecting the DNA repair system and explore the efficacy and safety of existing fertility preservation strategies in these patients.
Lingua originaleEnglish
pagine (da-a)332-338
Numero di pagine7
RivistaInternational Journal of Gynecological Cancer
Volume31
DOI
Stato di pubblicazionePubblicato - 2021

Keywords

  • BRCA1 protein
  • BRCA2 protein
  • lynch syndrome II

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