Fecal microbiota transplantation in gastrointestinal and extraintestinal disorders

Gianluca Ianiro, Antonio Gasbarrini, Giovanni Cammarota, Serena Porcari, Jonathan P Segal, Benjamin H Mullish, Mohammed N Quraishi

Risultato della ricerca: Contributo in rivistaArticolo in rivista

Abstract

Fecal microbiota transplantation (FMT) is the infusion of feces from a healthy donor into the gut of a recipient to treat a dysbiosis-related disease. FMT has been proven to be a safe and effective treatment for Clostridioides difficile infection, but increasing evidence supports the role of FMT in other gastrointestinal and extraintestinal diseases. The aim of this review is to paint the landscape of current evidence of FMT in different fields of application (including irritable bowel syndrome, inflammatory bowel disease, liver disorders, decolonization of multidrug-resistant bacteria, metabolic disorders and neurological disorders), as well as to discuss the current regulatory scenario of FMT, and hypothesize future directions of FMT.
Lingua originaleEnglish
pagine (da-a)1173-1186
Numero di pagine14
RivistaFuture Microbiology
Volume15
DOI
Stato di pubblicazionePubblicato - 2020

Keywords

  • cancer
  • Fecal Microbiota Transplantation
  • fecal microbiota transplantation
  • inflammatory bowel disease
  • irritable bowel syndrome
  • metabolic syndrome
  • microbiome
  • microbiota
  • Animals
  • Gastrointestinal Microbiome
  • Humans
  • Intestinal Diseases
  • Metabolic Diseases
  • Nervous System Diseases
  • Clostridium difficile

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