TY - JOUR
T1 - Fatigue and apathy in patients on chronic hemodialysis
AU - Bossola, Maurizio
AU - Di Stasio, Enrico
AU - Monteburini, Tania
AU - Santarelli, Stefano
AU - Cenerelli, Stefano
AU - Manes, Massimo
AU - Parodi, Emanuele Luigi
AU - Angioletti, Laura
AU - Balconi, Michela
PY - 2022
Y1 - 2022
N2 - Introduction: This study explores the link between fatigue and apathy in patients on chronic hemodialysis (HD). Methods: One hundred thirty-nine chronic HD patients underwent the assessment of fatigue, apathy, depression, and their functional status, with the fatigue severity scale (FSS), the Apathy Evaluation Scale (AES), the beck depression inventory (BDI), the activity of daily living (ADL), and instrumental activity of daily living (IADL). Results: Patients with high FSS had a significantly lower ADL and IADL score, higher BDI, Charlson Comorbidity Index, and AES score, and lower serum levels of creatinine, compared to low FSS patients. FSS was highly correlated with the AES, as well as with the BDI and the AES correlates with the BDI. At multiple regression analyses, only apathy and IADL were independent predictor variables of fatigue in HD population. Conclusion: Future longitudinal studies could determine if apathy is a causative factor for fatigue manifestation and development in HD patients.
AB - Introduction: This study explores the link between fatigue and apathy in patients on chronic hemodialysis (HD). Methods: One hundred thirty-nine chronic HD patients underwent the assessment of fatigue, apathy, depression, and their functional status, with the fatigue severity scale (FSS), the Apathy Evaluation Scale (AES), the beck depression inventory (BDI), the activity of daily living (ADL), and instrumental activity of daily living (IADL). Results: Patients with high FSS had a significantly lower ADL and IADL score, higher BDI, Charlson Comorbidity Index, and AES score, and lower serum levels of creatinine, compared to low FSS patients. FSS was highly correlated with the AES, as well as with the BDI and the AES correlates with the BDI. At multiple regression analyses, only apathy and IADL were independent predictor variables of fatigue in HD population. Conclusion: Future longitudinal studies could determine if apathy is a causative factor for fatigue manifestation and development in HD patients.
KW - apathy
KW - depression
KW - end-stage renal disease
KW - fatigue
KW - hemodialysis
KW - apathy
KW - depression
KW - end-stage renal disease
KW - fatigue
KW - hemodialysis
UR - http://hdl.handle.net/10807/227823
U2 - 10.1111/1744-9987.13784
DO - 10.1111/1744-9987.13784
M3 - Article
SN - 1744-9979
VL - 26
SP - 932
EP - 940
JO - Therapeutic Apheresis and Dialysis
JF - Therapeutic Apheresis and Dialysis
ER -