Fas-FasL interactions: A common pathogenetic mechanism in organ-specific autoimmunity

Risultato della ricerca: Contributo in rivistaArticolo in rivista

116 Citazioni (Scopus)

Abstract

Organ-specific autoimmunity is characterized by the accelerated loss of selected cell types, resulting in specific tissue destruction and disease. The role of different genetic or environmental factors in initiating the autoimmune reactivity is still unclear. However, novel mechanisms responsible for tissue destruction have recently been revealed. Here, Ruggero De Maria and Roberto Testi propose that Fas ligand may represent a common weapon during the destructive phase of organ-specific autoimmunity.
Lingua originaleEnglish
pagine (da-a)121-125
Numero di pagine5
RivistaImmunology Today
Volume19
DOI
Stato di pubblicazionePubblicato - 1998

Keywords

  • Immunology

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