Factors Predicting Ischemic-Type Biliary Lesions (ITBLs) After Liver Transplantation.

Alfonso Wolfango Avolio; Gabriele Sganga; F Frongillo; U Grossi; E Nure; G Pepe; G Bianco; Mc Lirosi; S. Agnes

Factors Predicting Ischemic-Type Biliary Lesions (ITBLs) After Liver Transplantation.

Alfonso Wolfango Avolio, Gabriele Sganga, F Frongillo, U Grossi, E Nure, G Pepe, G Bianco, Mc Lirosi, S. Agnes

Risultato della ricerca: Contributo in rivista › Articolo in rivista

Abstract

Among biliary complications, ischemic-type biliary lesions (ITBLs) remain a major cause of morbidity in liver transplant recipients, significantly affecting the chance of survival of both patients and grafts. We retrospectively reviewed 10 years of prospectively collected donor and recipient data from April 2001 to April 2011. We evaluated the incidence of ITBL occurrence, exploring the possible predisposing factors, including donor and recipient data. Two hundred fifty-one grafts were harvested: 222 of them were transplanted at our institution, the remaining 29 (11.6%) discarded by our donor team as showing >40% macrovesicular steatosis. Mild-moderate (20%-40%) macrovesicular steatosis (P < .001) and cold ischemia time (P = .048) significantly increased the risk of ITBL, also as an independent risk factor after multivariate analysis

Lingua originale	English
pagine (da-a)	2002-2004
Numero di pagine	3
Rivista	Transplantation Proceedings
Stato di pubblicazione	Pubblicato - 2012

Keywords

biliary lesion in liver transplantation

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title = "Factors Predicting Ischemic-Type Biliary Lesions (ITBLs) After Liver Transplantation.",

abstract = "Among biliary complications, ischemic-type biliary lesions (ITBLs) remain a major cause of morbidity in liver transplant recipients, significantly affecting the chance of survival of both patients and grafts. We retrospectively reviewed 10 years of prospectively collected donor and recipient data from April 2001 to April 2011. We evaluated the incidence of ITBL occurrence, exploring the possible predisposing factors, including donor and recipient data. Two hundred fifty-one grafts were harvested: 222 of them were transplanted at our institution, the remaining 29 (11.6%) discarded by our donor team as showing >40% macrovesicular steatosis. Mild-moderate (20%-40%) macrovesicular steatosis (P < .001) and cold ischemia time (P = .048) significantly increased the risk of ITBL, also as an independent risk factor after multivariate analysis",

keywords = "biliary lesion in liver transplantation, biliary lesion in liver transplantation",

author = "Avolio, {Alfonso Wolfango} and Gabriele Sganga and F Frongillo and U Grossi and E Nure and G Pepe and G Bianco and Mc Lirosi and S. Agnes",

year = "2012",

language = "English",

pages = "2002--2004",

journal = "Transplantation Proceedings",

issn = "0041-1345",

publisher = "Elsevier Science Incorporated / NY Journals:Madison Square Station, PO Box 882:New York, NY 10159:(212)633-3730, EMAIL: usinfo-f@elsevier.com, INTERNET: http://www.elsevier.com, Fax: (212)633-3680",

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TY - JOUR

T1 - Factors Predicting Ischemic-Type Biliary Lesions (ITBLs) After Liver Transplantation.

AU - Avolio, Alfonso Wolfango

AU - Sganga, Gabriele

AU - Frongillo, F

AU - Grossi, U

AU - Nure, E

AU - Pepe, G

AU - Bianco, G

AU - Lirosi, Mc

AU - Agnes, S.

PY - 2012

Y1 - 2012

N2 - Among biliary complications, ischemic-type biliary lesions (ITBLs) remain a major cause of morbidity in liver transplant recipients, significantly affecting the chance of survival of both patients and grafts. We retrospectively reviewed 10 years of prospectively collected donor and recipient data from April 2001 to April 2011. We evaluated the incidence of ITBL occurrence, exploring the possible predisposing factors, including donor and recipient data. Two hundred fifty-one grafts were harvested: 222 of them were transplanted at our institution, the remaining 29 (11.6%) discarded by our donor team as showing >40% macrovesicular steatosis. Mild-moderate (20%-40%) macrovesicular steatosis (P < .001) and cold ischemia time (P = .048) significantly increased the risk of ITBL, also as an independent risk factor after multivariate analysis

AB - Among biliary complications, ischemic-type biliary lesions (ITBLs) remain a major cause of morbidity in liver transplant recipients, significantly affecting the chance of survival of both patients and grafts. We retrospectively reviewed 10 years of prospectively collected donor and recipient data from April 2001 to April 2011. We evaluated the incidence of ITBL occurrence, exploring the possible predisposing factors, including donor and recipient data. Two hundred fifty-one grafts were harvested: 222 of them were transplanted at our institution, the remaining 29 (11.6%) discarded by our donor team as showing >40% macrovesicular steatosis. Mild-moderate (20%-40%) macrovesicular steatosis (P < .001) and cold ischemia time (P = .048) significantly increased the risk of ITBL, also as an independent risk factor after multivariate analysis

KW - biliary lesion in liver transplantation

UR - http://hdl.handle.net/10807/31362

M3 - Article

SP - 2002

EP - 2004

JO - Transplantation Proceedings

JF - Transplantation Proceedings

SN - 0041-1345

ER -