TY - JOUR
T1 - Extracorporeal photopheresis for paediatric patients experiencing graft-versus-host disease (GVHD)
AU - Rutella, Sergio
AU - Valentini, Caterina Giovanna
AU - Ceccarelli, Stefano
AU - Romano, Maria Teresa
AU - Brescia, Letizia P.
AU - Milano, Giuseppe Maria
AU - Locatelli, Franco
PY - 2014
Y1 - 2014
N2 - Extracorporeal photopheresis (ECP) is broadly used in adults with cutaneous T-cell lymphoma, acute or chronic graft-versus-host disease (GVHD), rejection of solid organ transplants, and a variety of autoimmune, cell-mediated diseases. The predominant use of ECP in children and adolescents is for treating GVHD. Children pose specific challenges to ECP, due to their unique physiology and to patient's size. Herein, we will focus on current clinical trials with ECP in children with GVHD, with an emphasis on technical and clinical issues that are peculiar to the paediatric setting. (C) 2014 Elsevier Ltd. All rights reserved.
AB - Extracorporeal photopheresis (ECP) is broadly used in adults with cutaneous T-cell lymphoma, acute or chronic graft-versus-host disease (GVHD), rejection of solid organ transplants, and a variety of autoimmune, cell-mediated diseases. The predominant use of ECP in children and adolescents is for treating GVHD. Children pose specific challenges to ECP, due to their unique physiology and to patient's size. Herein, we will focus on current clinical trials with ECP in children with GVHD, with an emphasis on technical and clinical issues that are peculiar to the paediatric setting. (C) 2014 Elsevier Ltd. All rights reserved.
KW - Childhood leukemia
KW - Graft-versus-host disease
KW - Stem cell transplantation
KW - Solid organ transplantation
KW - Photopheresis
KW - Childhood leukemia
KW - Graft-versus-host disease
KW - Stem cell transplantation
KW - Solid organ transplantation
KW - Photopheresis
UR - http://hdl.handle.net/10807/242598
U2 - 10.1016/j.transci.2014.04.004
DO - 10.1016/j.transci.2014.04.004
M3 - Article
SN - 1473-0502
VL - 50
SP - 340
EP - 348
JO - Transfusion and Apheresis Science
JF - Transfusion and Apheresis Science
ER -