Expression of the stem cell marker CD133 in recurrent glioblastoma and its value for prognosis

Roberto Pallini; Lucia Ricci Vitiani; Nicola Montano; Cristina Mollinari; Mauro Biffoni; Tonia Cenci; Francesco Pierconti; Maurizio Martini; Ruggero De Maria; Luigi Maria Larocca

doi:10.1002/cncr.25581

Expression of the stem cell marker CD133 in recurrent glioblastoma and its value for prognosis

Roberto Pallini
, Lucia Ricci Vitiani
, Nicola Montano
, Cristina Mollinari
, Mauro Biffoni
, Tonia Cenci
, Francesco Pierconti
, Maurizio Martini
, Ruggero De Maria
, Luigi Maria Larocca

Risultato della ricerca: Contributo in rivista › Articolo

80 Citazioni (Scopus)

Abstract

Experimental data suggest that glioblastoma cells expressing the stem cell marker CD133 play a major role in radiochemoresistance and tumor aggressiveness. To date, however, there is no clinical evidence that the fraction of CD133-positive cells in glioblastoma that recurs after radiochemotherapy may be relevant for prognosis.

Lingua originale	Inglese
pagine (da-a)	162-174
Numero di pagine	13
Rivista	Cancer
Volume	117
DOI	https://doi.org/10.1002/cncr.25581
Stato di pubblicazione	Pubblicato - 2011

Keywords

Adult
Aged
Antigens, CD
Brain Neoplasms
Female
Glioblastoma
Glycoproteins
Humans
Male
Middle Aged
Neoplastic Stem Cells
Neural Stem Cells
Peptides
Prognosis
Recurrence
Tumor Markers, Biological

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10.1002/cncr.25581

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title = "Expression of the stem cell marker CD133 in recurrent glioblastoma and its value for prognosis",

abstract = "Experimental data suggest that glioblastoma cells expressing the stem cell marker CD133 play a major role in radiochemoresistance and tumor aggressiveness. To date, however, there is no clinical evidence that the fraction of CD133-positive cells in glioblastoma that recurs after radiochemotherapy may be relevant for prognosis.",

keywords = "Adult, Aged, Antigens, CD, Brain Neoplasms, Female, Glioblastoma, Glycoproteins, Humans, Male, Middle Aged, Neoplastic Stem Cells, Neural Stem Cells, Peptides, Prognosis, Recurrence, Tumor Markers, Biological, Adult, Aged, Antigens, CD, Brain Neoplasms, Female, Glioblastoma, Glycoproteins, Humans, Male, Middle Aged, Neoplastic Stem Cells, Neural Stem Cells, Peptides, Prognosis, Recurrence, Tumor Markers, Biological",

author = "Roberto Pallini and \{Ricci Vitiani\}, Lucia and Nicola Montano and Cristina Mollinari and Mauro Biffoni and Tonia Cenci and Francesco Pierconti and Maurizio Martini and \{De Maria\}, Ruggero and Larocca, \{Luigi Maria\}",

year = "2011",

doi = "10.1002/cncr.25581",

language = "English",

volume = "117",

pages = "162--174",

journal = "Cancer",

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publisher = "John Wiley and Sons Inc.",

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TY - JOUR

T1 - Expression of the stem cell marker CD133 in recurrent glioblastoma and its value for prognosis

AU - Pallini, Roberto

AU - Ricci Vitiani, Lucia

AU - Montano, Nicola

AU - Mollinari, Cristina

AU - Biffoni, Mauro

AU - Cenci, Tonia

AU - Pierconti, Francesco

AU - Martini, Maurizio

AU - De Maria, Ruggero

AU - Larocca, Luigi Maria

PY - 2011

Y1 - 2011

N2 - Experimental data suggest that glioblastoma cells expressing the stem cell marker CD133 play a major role in radiochemoresistance and tumor aggressiveness. To date, however, there is no clinical evidence that the fraction of CD133-positive cells in glioblastoma that recurs after radiochemotherapy may be relevant for prognosis.

AB - Experimental data suggest that glioblastoma cells expressing the stem cell marker CD133 play a major role in radiochemoresistance and tumor aggressiveness. To date, however, there is no clinical evidence that the fraction of CD133-positive cells in glioblastoma that recurs after radiochemotherapy may be relevant for prognosis.

KW - Adult

KW - Aged

KW - Antigens, CD

KW - Brain Neoplasms

KW - Female

KW - Glioblastoma

KW - Glycoproteins

KW - Humans

KW - Male

KW - Middle Aged

KW - Neoplastic Stem Cells

KW - Neural Stem Cells

KW - Peptides

KW - Prognosis

KW - Recurrence

KW - Tumor Markers, Biological

KW - Adult

KW - Aged

KW - Antigens, CD

KW - Brain Neoplasms

KW - Female

KW - Glioblastoma

KW - Glycoproteins

KW - Humans

KW - Male

KW - Middle Aged

KW - Neoplastic Stem Cells

KW - Neural Stem Cells

KW - Peptides

KW - Prognosis

KW - Recurrence

KW - Tumor Markers, Biological

UR - http://hdl.handle.net/10807/25858

U2 - 10.1002/cncr.25581

DO - 10.1002/cncr.25581

M3 - Article

SN - 0008-543X

VL - 117

SP - 162

EP - 174

JO - Cancer

JF - Cancer

ER -

Expression of the stem cell marker CD133 in recurrent glioblastoma and its value for prognosis

Abstract

Keywords

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