Expression of the stem cell marker CD133 in recurrent glioblastoma and its value for prognosis

Roberto Pallini, Nicola Montano, Francesco Pierconti, Maurizio Martini, Luigi Maria Larocca, Tonia Cenci, Lucia Ricci Vitiani, Cristina Mollinari, Mauro Biffoni, Ruggero De Maria

Risultato della ricerca: Contributo in rivistaArticolo in rivista

80 Citazioni (Scopus)

Abstract

Experimental data suggest that glioblastoma cells expressing the stem cell marker CD133 play a major role in radiochemoresistance and tumor aggressiveness. To date, however, there is no clinical evidence that the fraction of CD133-positive cells in glioblastoma that recurs after radiochemotherapy may be relevant for prognosis.
Lingua originaleEnglish
pagine (da-a)162-174
Numero di pagine13
RivistaCancer
Volume117
DOI
Stato di pubblicazionePubblicato - 2011

Keywords

  • Adult
  • Aged
  • Antigens, CD
  • Brain Neoplasms
  • Female
  • Glioblastoma
  • Glycoproteins
  • Humans
  • Male
  • Middle Aged
  • Neoplastic Stem Cells
  • Neural Stem Cells
  • Peptides
  • Prognosis
  • Recurrence
  • Tumor Markers, Biological

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