Exposure to thoracic dust, airway symptoms and lung function in cement production workers

Antonio Bergamaschi, K Nordby, Akm Fell, H Notø, W Eduard, M Skogstad, Y Thomassen, J Kongerud, H. Kjuus

Risultato della ricerca: Contributo in rivistaArticolo in rivista

35 Citazioni (Scopus)

Abstract

Cement dust exposure has previously been associated with airway symptoms and ventilatory impairment. The aim of the present study was to examine lung function and airway symptoms among employees in different jobs and at different levels of exposure to thoracic dust in the cement production industry. At the start of a 4-yr prospective cohort study in 2007, exposure to cement dust, symptoms and lung function were recorded cross-sectionally in 4,265 employees in 24 European cement plants. Bronchial exposure was assessed by 2,670 full-shift dust samples with cyclones collecting the thoracic aerosol fraction. A job exposure matrix was constructed by grouping dust concentrations according to job type and plant. Elevated odds ratios for symptoms and airflow limitation (range 1.2-2.6 in the highest quartile), but not for chronic bronchitis, were found in the higher quartiles of exposure compared with the lowest quartile. Forced expiratory volume in 1 s (FEV(1)) showed an exposure-response relationship with a 270-mL deficit of FEV(1) (95% CI 190-300 mL) in the highest compared with the lowest exposure level. The results support the hypothesis that exposure to dust in cement production may lead to respiratory symptoms and airway obstruction.
Lingua originaleEnglish
pagine (da-a)1278-1286
Numero di pagine9
RivistaThe European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology
Volume38
DOI
Stato di pubblicazionePubblicato - 2011
Pubblicato esternamenteYes

Keywords

  • Adult
  • Air Pollutants, Occupational
  • Airway Obstruction
  • Bronchitis, Chronic
  • Cohort Studies
  • Construction Materials
  • Dust
  • Europe
  • Female
  • Humans
  • Inhalation Exposure
  • Lung
  • Male
  • Middle Aged
  • Occupational Diseases
  • Occupational Exposure
  • Prospective Studies
  • Respiratory Function Tests
  • Smoking
  • Spirometry

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