Experimental models of early exposure to alcohol: a way to unravel the neurobiology of mental retardation

Alberto Granato, Andrea De Giorgio

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

2 Citazioni (Scopus)

Abstract

As of November 2014, a PubMed search for “fetal alcohol” retrieved more than 14,500 articles. Alcohol consumption during pregnancy and its detrimental consequences on the developing brain raise major public health, social, and economic issues. However, the research on fetal alcohol spectrum disorders (FASD) in the real world is challenging, given that it is largely based on retrospective analysis. Therefore, establishing the relationship between brain damage and drinking habits proves particularly hard. One of the advantages of FASD studies carried out in the laboratory environment derives from the tight control of time, dose, and modality of alcohol exposure.
Lingua originaleEnglish
pagine (da-a)1-2
Numero di pagine2
RivistaFrontiers in Pediatrics
Volume2
DOI
Stato di pubblicazionePubblicato - 2015

Keywords

  • amygdala
  • apoptosis
  • cerebral cortex
  • development
  • epigenetics
  • fetal alcohol spectrum disorders
  • glial cells
  • intellectual disability

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