Evolution of transmitted HIV-1 drug resistance in HIV-1-infected patients in Italy from 2000 to 2010.

Manuela Colafigli; Carlo Torti; Enrico Maria Trecarichi; L. Albini; A. Rosi; V. Micheli; N. Manca; G. Penco; B. Bruzzone; G. Punzi; P. Corsi; G. Parruti; P. Bagnarelli; L. Monno; A. Gonnelli; Roberto Cauda; Simona Di Giambenedetto

doi:10.1111/j.1469-0691.2012.03847.x

Evolution of transmitted HIV-1 drug resistance in HIV-1-infected patients in Italy from 2000 to 2010.

Manuela Colafigli
, Carlo Torti
, Enrico Maria Trecarichi
, L. Albini
, A. Rosi
, V. Micheli
, N. Manca
, G. Penco
, B. Bruzzone
, G. Punzi
, P. Corsi
, G. Parruti
, P. Bagnarelli
, L. Monno
, A. Gonnelli
, Roberto Cauda
, Simona Di Giambenedetto

University of Brescia
University of Siena
University of Milan
E.O. Ospedali Galliera
San Martino Hospital Genoa
University of Bari
Azienda Ospedaliera Careggi
Hospital of Pescara
Marche Polytechnic University
Azienda Ospedaliera Universitaria Senese

Risultato della ricerca: Contributo in rivista › Articolo

24 Citazioni (Scopus)

Abstract

Prevalence and predictors of transmitted drug resistance (TDR), defined as the presence of at least one WHO surveillance drug resistance mutation (SDRM), were investigated in antiretroviral naı ¨ve HIV-1-infected patients, with a genotypic resistance test (GRT) performed £6 months before starting cART between 2000 and 2010. 3163 HIV-1 sequences were selected (69% subtype B). Overall, the prevalence of TDR was 12% (13.2% subtype B, 9% non-B). TDR significantly declined overall and for the single drug classes. Older age independently predicted increased odds of TDR, whereas a more recent GRT, a higher HIV-RNA

Lingua originale	Inglese
pagine (da-a)	299-304
Numero di pagine	6
Rivista	Clinical Microbiology and Infection
DOI	https://doi.org/10.1111/j.1469-0691.2012.03847.x
Stato di pubblicazione	Pubblicato - 2012

OSS delle Nazioni Unite

Questo processo contribuisce al raggiungimento dei seguenti obiettivi di sviluppo sostenibile

SDG 3 Salute e benessere

Keywords

HAART
HIV

Accesso al documento

10.1111/j.1469-0691.2012.03847.x

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Colafigli, M., Torti, C., Trecarichi, E. M., Albini, L., Rosi, A., Micheli, V., Manca, N., Penco, G., Bruzzone, B., Punzi, G., Corsi, P., Parruti, G., Bagnarelli, P., Monno, L., Gonnelli, A., Cauda, R., & Di Giambenedetto, S. (2012). Evolution of transmitted HIV-1 drug resistance in HIV-1-infected patients in Italy from 2000 to 2010. Clinical Microbiology and Infection, 299-304. https://doi.org/10.1111/j.1469-0691.2012.03847.x

@article{30fd154ebeb74ea2a50f6ca1a8d38eb9,

title = "Evolution of transmitted HIV-1 drug resistance in HIV-1-infected patients in Italy from 2000 to 2010.",

abstract = "Prevalence and predictors of transmitted drug resistance (TDR), defined as the presence of at least one WHO surveillance drug resistance mutation (SDRM), were investigated in antiretroviral naı ¨ve HIV-1-infected patients, with a genotypic resistance test (GRT) performed £6 months before starting cART between 2000 and 2010. 3163 HIV-1 sequences were selected (69\% subtype B). Overall, the prevalence of TDR was 12\% (13.2\% subtype B, 9\% non-B). TDR significantly declined overall and for the single drug classes. Older age independently predicted increased odds of TDR, whereas a more recent GRT, a higher HIV-RNA",

keywords = "HAART, HIV, HAART, HIV",

author = "Manuela Colafigli and Carlo Torti and Trecarichi, \{Enrico Maria\} and L. Albini and A. Rosi and V. Micheli and N. Manca and G. Penco and B. Bruzzone and G. Punzi and P. Corsi and G. Parruti and P. Bagnarelli and L. Monno and A. Gonnelli and Roberto Cauda and \{Di Giambenedetto\}, Simona",

year = "2012",

doi = "10.1111/j.1469-0691.2012.03847.x",

language = "English",

pages = "299--304",

journal = "Clinical Microbiology and Infection",

issn = "1198-743X",

publisher = "Elsevier B.V.",

}

Colafigli, M, Torti, C, Trecarichi, EM, Albini, L, Rosi, A, Micheli, V, Manca, N, Penco, G, Bruzzone, B, Punzi, G, Corsi, P, Parruti, G, Bagnarelli, P, Monno, L, Gonnelli, A, Cauda, R & Di Giambenedetto, S 2012, 'Evolution of transmitted HIV-1 drug resistance in HIV-1-infected patients in Italy from 2000 to 2010.', Clinical Microbiology and Infection, pagg. 299-304. https://doi.org/10.1111/j.1469-0691.2012.03847.x

TY - JOUR

T1 - Evolution of transmitted HIV-1 drug resistance in HIV-1-infected patients in Italy from 2000 to 2010.

AU - Colafigli, Manuela

AU - Torti, Carlo

AU - Trecarichi, Enrico Maria

AU - Albini, L.

AU - Rosi, A.

AU - Micheli, V.

AU - Manca, N.

AU - Penco, G.

AU - Bruzzone, B.

AU - Punzi, G.

AU - Corsi, P.

AU - Parruti, G.

AU - Bagnarelli, P.

AU - Monno, L.

AU - Gonnelli, A.

AU - Cauda, Roberto

AU - Di Giambenedetto, Simona

PY - 2012

Y1 - 2012

N2 - Prevalence and predictors of transmitted drug resistance (TDR), defined as the presence of at least one WHO surveillance drug resistance mutation (SDRM), were investigated in antiretroviral naı ¨ve HIV-1-infected patients, with a genotypic resistance test (GRT) performed £6 months before starting cART between 2000 and 2010. 3163 HIV-1 sequences were selected (69% subtype B). Overall, the prevalence of TDR was 12% (13.2% subtype B, 9% non-B). TDR significantly declined overall and for the single drug classes. Older age independently predicted increased odds of TDR, whereas a more recent GRT, a higher HIV-RNA

AB - Prevalence and predictors of transmitted drug resistance (TDR), defined as the presence of at least one WHO surveillance drug resistance mutation (SDRM), were investigated in antiretroviral naı ¨ve HIV-1-infected patients, with a genotypic resistance test (GRT) performed £6 months before starting cART between 2000 and 2010. 3163 HIV-1 sequences were selected (69% subtype B). Overall, the prevalence of TDR was 12% (13.2% subtype B, 9% non-B). TDR significantly declined overall and for the single drug classes. Older age independently predicted increased odds of TDR, whereas a more recent GRT, a higher HIV-RNA

KW - HAART

KW - HIV

KW - HAART

KW - HIV

UR - http://hdl.handle.net/10807/29003

U2 - 10.1111/j.1469-0691.2012.03847.x

DO - 10.1111/j.1469-0691.2012.03847.x

M3 - Article

SN - 1198-743X

SP - 299

EP - 304

JO - Clinical Microbiology and Infection

JF - Clinical Microbiology and Infection

ER -

Evolution of transmitted HIV-1 drug resistance in HIV-1-infected patients in Italy from 2000 to 2010.

Abstract

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