Abstract
Prevalence and predictors of transmitted drug resistance (TDR),
defined as the presence of at least one WHO surveillance drug
resistance mutation (SDRM), were investigated in antiretroviral naı
¨ve HIV-1-infected patients, with a genotypic resistance test
(GRT) performed £6 months before starting cART between
2000 and 2010. 3163 HIV-1 sequences were selected (69% subtype
B). Overall, the prevalence of TDR was 12% (13.2% subtype
B, 9% non-B). TDR significantly declined overall and for the
single drug classes. Older age independently predicted increased
odds of TDR, whereas a more recent GRT, a higher HIV-RNA
Lingua originale | English |
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pagine (da-a) | 299-304 |
Numero di pagine | 6 |
Rivista | Clinical Microbiology and Infection |
Stato di pubblicazione | Pubblicato - 2012 |
Keywords
- HAART
- HIV