Evolution of transmitted HIV-1 drug resistance in HIV-1-infected patients in Italy from 2000 to 2010.

Roberto Cauda; Simona Di Giambenedetto; Manuela Colafigli; Enrico Maria Trecarichi; Carlo Torti; Laura Albini; Andrea Rosi; Valeria Micheli; Nino Manca; Giovanni Penco; Bianca Bruzzone; Grazia Punzi; Paola Corsi; Giustino Parruti; Patrizia Bagnaelli; Laura Monno; Angela Gonnelli

Evolution of transmitted HIV-1 drug resistance in HIV-1-infected patients in Italy from 2000 to 2010.

Roberto Cauda, Simona Di Giambenedetto, Manuela Colafigli, Enrico Maria Trecarichi, Carlo Torti, Laura Albini, Andrea Rosi, Valeria Micheli, Nino Manca, Giovanni Penco, Bianca Bruzzone, Grazia Punzi, Paola Corsi, Giustino Parruti, Patrizia Bagnaelli, Laura Monno, Angela Gonnelli

Risultato della ricerca: Contributo in rivista › Articolo in rivista

23 Citazioni (Scopus)

Abstract

Prevalence and predictors of transmitted drug resistance (TDR), defined as the presence of at least one WHO surveillance drug resistance mutation (SDRM), were investigated in antiretroviral naı ¨ve HIV-1-infected patients, with a genotypic resistance test (GRT) performed £6 months before starting cART between 2000 and 2010. 3163 HIV-1 sequences were selected (69% subtype B). Overall, the prevalence of TDR was 12% (13.2% subtype B, 9% non-B). TDR significantly declined overall and for the single drug classes. Older age independently predicted increased odds of TDR, whereas a more recent GRT, a higher HIV-RNA

Lingua originale	English
pagine (da-a)	299-304
Numero di pagine	6
Rivista	Clinical Microbiology and Infection
Stato di pubblicazione	Pubblicato - 2012

Keywords

HAART
HIV

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Cauda, R., Di Giambenedetto, S., Colafigli, M., Trecarichi, E. M., Torti, C., Albini, L., Rosi, A., Micheli, V., Manca, N., Penco, G., Bruzzone, B., Punzi, G., Corsi, P., Parruti, G., Bagnaelli, P., Monno, L., & Gonnelli, A. (2012). Evolution of transmitted HIV-1 drug resistance in HIV-1-infected patients in Italy from 2000 to 2010. Clinical Microbiology and Infection, 299-304.

Cauda, Roberto ; Di Giambenedetto, Simona ; Colafigli, Manuela ; Trecarichi, Enrico Maria ; Torti, Carlo ; Albini, Laura ; Rosi, Andrea ; Micheli, Valeria ; Manca, Nino ; Penco, Giovanni ; Bruzzone, Bianca ; Punzi, Grazia ; Corsi, Paola ; Parruti, Giustino ; Bagnaelli, Patrizia ; Monno, Laura ; Gonnelli, Angela. / Evolution of transmitted HIV-1 drug resistance in HIV-1-infected patients in Italy from 2000 to 2010. In: Clinical Microbiology and Infection. 2012 ; pagg. 299-304.

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title = "Evolution of transmitted HIV-1 drug resistance in HIV-1-infected patients in Italy from 2000 to 2010.",

abstract = "Prevalence and predictors of transmitted drug resistance (TDR), defined as the presence of at least one WHO surveillance drug resistance mutation (SDRM), were investigated in antiretroviral naı ¨ve HIV-1-infected patients, with a genotypic resistance test (GRT) performed £6 months before starting cART between 2000 and 2010. 3163 HIV-1 sequences were selected (69% subtype B). Overall, the prevalence of TDR was 12% (13.2% subtype B, 9% non-B). TDR significantly declined overall and for the single drug classes. Older age independently predicted increased odds of TDR, whereas a more recent GRT, a higher HIV-RNA",

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author = "Roberto Cauda and {Di Giambenedetto}, Simona and Manuela Colafigli and Trecarichi, {Enrico Maria} and Carlo Torti and Laura Albini and Andrea Rosi and Valeria Micheli and Nino Manca and Giovanni Penco and Bianca Bruzzone and Grazia Punzi and Paola Corsi and Giustino Parruti and Patrizia Bagnaelli and Laura Monno and Angela Gonnelli",

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Evolution of transmitted HIV-1 drug resistance in HIV-1-infected patients in Italy from 2000 to 2010. / Cauda, Roberto ; Di Giambenedetto, Simona; Colafigli, Manuela; Trecarichi, Enrico Maria; Torti, Carlo; Albini, Laura; Rosi, Andrea; Micheli, Valeria; Manca, Nino; Penco, Giovanni; Bruzzone, Bianca; Punzi, Grazia; Corsi, Paola; Parruti, Giustino; Bagnaelli, Patrizia; Monno, Laura; Gonnelli, Angela.

In: Clinical Microbiology and Infection, 2012, pag. 299-304.

Risultato della ricerca: Contributo in rivista › Articolo in rivista

TY - JOUR

T1 - Evolution of transmitted HIV-1 drug resistance in HIV-1-infected patients in Italy from 2000 to 2010.

AU - Cauda, Roberto

AU - Di Giambenedetto, Simona

AU - Colafigli, Manuela

AU - Trecarichi, Enrico Maria

AU - Torti, Carlo

AU - Albini, Laura

AU - Rosi, Andrea

AU - Micheli, Valeria

AU - Manca, Nino

AU - Penco, Giovanni

AU - Bruzzone, Bianca

AU - Punzi, Grazia

AU - Corsi, Paola

AU - Parruti, Giustino

AU - Bagnaelli, Patrizia

AU - Monno, Laura

AU - Gonnelli, Angela

PY - 2012

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AB - Prevalence and predictors of transmitted drug resistance (TDR), defined as the presence of at least one WHO surveillance drug resistance mutation (SDRM), were investigated in antiretroviral naı ¨ve HIV-1-infected patients, with a genotypic resistance test (GRT) performed £6 months before starting cART between 2000 and 2010. 3163 HIV-1 sequences were selected (69% subtype B). Overall, the prevalence of TDR was 12% (13.2% subtype B, 9% non-B). TDR significantly declined overall and for the single drug classes. Older age independently predicted increased odds of TDR, whereas a more recent GRT, a higher HIV-RNA

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KW - HIV

KW - HAART

KW - HIV

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