Evidence-based guidelines for the pharmacological treatment of migraine

Raffaele Ornello; Valeria Caponnetto; Fayyaz Ahmed; Haidar M Al-Khazali; Anna Ambrosini; Sait Ashina; Carlo Baraldi; Alessia Bellotti; Filippo Brighina; Paolo Calabresi; Francesco Casillo; Sabina Cevoli; Shuli Cheng; Chia-Chun Chiang; Alberto Chiarugi; Rune Häckert Christensen; Min Kyung Chu; Gianluca Coppola; Ilenia Corbelli; Santiago Crema; Roberto De Icco; Marina de Tommaso; Cherubino Di Lorenzo; Vincenzo Di Stefano; Hans-Christoph Diener; Esme Ekizoğlu; Adriana Fallacara; Valentina Favoni; Kimberly N Garces; Pierangelo Geppetti; Maria Teresa Goicochea; Antonio Granato; Franco Granella; Simona Guerzoni; Woo-Seok Ha; Amr Hassan; Koichi Hirata; Jan Hoffmann; Eva-Maria Hüssler; Mona Hussein; Luigi Francesco Iannone; Bronwyn Jenkins; Alejandro Labastida-Ramirez; Anna Laporta; Morris Levin; Antonino Lupica; Edoardo Mampreso; Daniele Martinelli; Teshamae S Monteith; Ilaria Orologio; Aynur Özge; Li-Ling Hope Pan; Lavindren Luke Panneerchelvam; Mario F P Peres; Marcio Nattan Portes Souza; Patricia Pozo-Rosich; Maria Pia Prudenzano; Silvia Quattrocchi; Innocenzo Rainero; Volodymyr Romanenko; Marina Romozzi; Antonio Russo; Grazia Sances; Paola Sarchielli; Todd J Schwedt; Marcello Silvestro; Diego Belandrino Swerts; Cristina Tassorelli; Alessandro Tessitore; Mansoureh Togha; Gloria Vaghi; Shuu-Jiun Wang; Messoud Ashina; Simona Sacco

doi:10.1177/03331024241305381

Evidence-based guidelines for the pharmacological treatment of migraine

Raffaele Ornello, Valeria Caponnetto, Fayyaz Ahmed, Haidar M Al-Khazali, Anna Ambrosini, Sait Ashina, Carlo Baraldi, Alessia Bellotti, Filippo Brighina, Paolo Calabresi, Francesco Casillo, Sabina Cevoli, Shuli Cheng, Chia-Chun Chiang, Alberto Chiarugi, Rune Häckert Christensen, Min Kyung Chu, Gianluca Coppola, Ilenia Corbelli, Santiago CremaRoberto De Icco, Marina de Tommaso, Cherubino Di Lorenzo, Vincenzo Di Stefano, Hans-Christoph Diener, Esme Ekizoğlu, Adriana Fallacara, Valentina Favoni, Kimberly N Garces, Pierangelo Geppetti, Maria Teresa Goicochea, Antonio Granato, Franco Granella, Simona Guerzoni, Woo-Seok Ha, Amr Hassan, Koichi Hirata, Jan Hoffmann, Eva-Maria Hüssler, Mona Hussein, Luigi Francesco Iannone, Bronwyn Jenkins, Alejandro Labastida-Ramirez, Anna Laporta, Morris Levin, Antonino Lupica, Edoardo Mampreso, Daniele Martinelli, Teshamae S Monteith, Ilaria Orologio, Aynur Özge, Li-Ling Hope Pan, Lavindren Luke Panneerchelvam, Mario F P Peres, Marcio Nattan Portes Souza, Patricia Pozo-Rosich, Maria Pia Prudenzano, Silvia Quattrocchi, Innocenzo Rainero, Volodymyr Romanenko, Marina Romozzi, Antonio Russo, Grazia Sances, Paola Sarchielli, Todd J Schwedt, Marcello Silvestro, Diego Belandrino Swerts, Cristina Tassorelli, Alessandro Tessitore, Mansoureh Togha, Gloria Vaghi, Shuu-Jiun Wang, Messoud Ashina, Simona Sacco

Risultato della ricerca: Contributo in rivista › Articolo

Abstract

: We here present evidence-based guidelines for the pharmacological treatment of migraine. These guidelines, created by the Italian Society for the Study of Headache and the International Headache Society, aim to offer clear, actionable recommendations to healthcare professionals. They incorporate evidence-based recommendations from randomized controlled trials and expert-based opinions. The guidelines follow the Grading of Recommendations, Assessment, Development and Evaluation approach for assessing the quality of evidence. The guideline development involved a systematic review of literature across multiple databases, adherence to Cochrane review methods, and a structured framework for data extraction and interpretation. Although the guidelines provide a robust foundation for migraine treatment, they also highlight gaps in current research, such as the paucity of head-to-head drug comparisons and the need for long-term outcome studies. These guidelines serve as a resource to standardize migraine treatment and promote high-quality care across different healthcare settings.

Lingua originale	Inglese
pagine (da-a)	N/A-N/A
Rivista	Cephalalgia
Volume	45
Numero di pubblicazione	4
DOI	https://doi.org/10.1177/03331024241305381
Stato di pubblicazione	Pubblicato - 2025

Keywords

acute treatment
drugs
migraine treatment
pharmacological treatments
preventive treatment

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10.1177/03331024241305381

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Ornello, R., Caponnetto, V., Ahmed, F., Al-Khazali, H. M., Ambrosini, A., Ashina, S., Baraldi, C., Bellotti, A., Brighina, F., Calabresi, P., Casillo, F., Cevoli, S., Cheng, S., Chiang, C.-C., Chiarugi, A., Christensen, R. H., Chu, M. K., Coppola, G., Corbelli, I., ... Sacco, S. (2025). Evidence-based guidelines for the pharmacological treatment of migraine. Cephalalgia, 45(4), N/A-N/A. https://doi.org/10.1177/03331024241305381

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title = "Evidence-based guidelines for the pharmacological treatment of migraine",

abstract = ": We here present evidence-based guidelines for the pharmacological treatment of migraine. These guidelines, created by the Italian Society for the Study of Headache and the International Headache Society, aim to offer clear, actionable recommendations to healthcare professionals. They incorporate evidence-based recommendations from randomized controlled trials and expert-based opinions. The guidelines follow the Grading of Recommendations, Assessment, Development and Evaluation approach for assessing the quality of evidence. The guideline development involved a systematic review of literature across multiple databases, adherence to Cochrane review methods, and a structured framework for data extraction and interpretation. Although the guidelines provide a robust foundation for migraine treatment, they also highlight gaps in current research, such as the paucity of head-to-head drug comparisons and the need for long-term outcome studies. These guidelines serve as a resource to standardize migraine treatment and promote high-quality care across different healthcare settings.",

keywords = "acute treatment, drugs, migraine treatment, pharmacological treatments, preventive treatment, acute treatment, drugs, migraine treatment, pharmacological treatments, preventive treatment",

author = "Raffaele Ornello and Valeria Caponnetto and Fayyaz Ahmed and Al-Khazali, \{Haidar M\} and Anna Ambrosini and Sait Ashina and Carlo Baraldi and Alessia Bellotti and Filippo Brighina and Paolo Calabresi and Francesco Casillo and Sabina Cevoli and Shuli Cheng and Chia-Chun Chiang and Alberto Chiarugi and Christensen, \{Rune H{\"a}ckert\} and Chu, \{Min Kyung\} and Gianluca Coppola and Ilenia Corbelli and Santiago Crema and \{De Icco\}, Roberto and \{de Tommaso\}, Marina and \{Di Lorenzo\}, Cherubino and \{Di Stefano\}, Vincenzo and Hans-Christoph Diener and Esme Ekizoğlu and Adriana Fallacara and Valentina Favoni and Garces, \{Kimberly N\} and Pierangelo Geppetti and Goicochea, \{Maria Teresa\} and Antonio Granato and Franco Granella and Simona Guerzoni and Woo-Seok Ha and Amr Hassan and Koichi Hirata and Jan Hoffmann and Eva-Maria H{\"u}ssler and Mona Hussein and Iannone, \{Luigi Francesco\} and Bronwyn Jenkins and Alejandro Labastida-Ramirez and Anna Laporta and Morris Levin and Antonino Lupica and Edoardo Mampreso and Daniele Martinelli and Monteith, \{Teshamae S\} and Ilaria Orologio and Aynur {\"O}zge and Pan, \{Li-Ling Hope\} and Panneerchelvam, \{Lavindren Luke\} and Peres, \{Mario F P\} and Souza, \{Marcio Nattan Portes\} and Patricia Pozo-Rosich and Prudenzano, \{Maria Pia\} and Silvia Quattrocchi and Innocenzo Rainero and Volodymyr Romanenko and Marina Romozzi and Antonio Russo and Grazia Sances and Paola Sarchielli and Schwedt, \{Todd J\} and Marcello Silvestro and Swerts, \{Diego Belandrino\} and Cristina Tassorelli and Alessandro Tessitore and Mansoureh Togha and Gloria Vaghi and Shuu-Jiun Wang and Messoud Ashina and Simona Sacco",

year = "2025",

doi = "10.1177/03331024241305381",

language = "English",

volume = "45",

pages = "N/A--N/A",

journal = "Cephalalgia",

issn = "0333-1024",

publisher = "SAGE Publications Ltd",

number = "4",

}

Ornello, R, Caponnetto, V, Ahmed, F, Al-Khazali, HM, Ambrosini, A, Ashina, S, Baraldi, C, Bellotti, A, Brighina, F, Calabresi, P, Casillo, F, Cevoli, S, Cheng, S, Chiang, C-C, Chiarugi, A, Christensen, RH, Chu, MK, Coppola, G, Corbelli, I, Crema, S, De Icco, R, de Tommaso, M, Di Lorenzo, C, Di Stefano, V, Diener, H-C, Ekizoğlu, E, Fallacara, A, Favoni, V, Garces, KN, Geppetti, P, Goicochea, MT, Granato, A, Granella, F, Guerzoni, S, Ha, W-S, Hassan, A, Hirata, K, Hoffmann, J, Hüssler, E-M, Hussein, M, Iannone, LF, Jenkins, B, Labastida-Ramirez, A, Laporta, A, Levin, M, Lupica, A, Mampreso, E, Martinelli, D, Monteith, TS, Orologio, I, Özge, A, Pan, L-LH, Panneerchelvam, LL, Peres, MFP, Souza, MNP, Pozo-Rosich, P, Prudenzano, MP, Quattrocchi, S, Rainero, I, Romanenko, V, Romozzi, M, Russo, A, Sances, G, Sarchielli, P, Schwedt, TJ, Silvestro, M, Swerts, DB, Tassorelli, C, Tessitore, A, Togha, M, Vaghi, G, Wang, S-J, Ashina, M & Sacco, S 2025, 'Evidence-based guidelines for the pharmacological treatment of migraine', Cephalalgia, vol. 45, n. 4, pagg. N/A-N/A. https://doi.org/10.1177/03331024241305381

TY - JOUR

T1 - Evidence-based guidelines for the pharmacological treatment of migraine

AU - Ornello, Raffaele

AU - Caponnetto, Valeria

AU - Ahmed, Fayyaz

AU - Al-Khazali, Haidar M

AU - Ambrosini, Anna

AU - Ashina, Sait

AU - Baraldi, Carlo

AU - Bellotti, Alessia

AU - Brighina, Filippo

AU - Calabresi, Paolo

AU - Casillo, Francesco

AU - Cevoli, Sabina

AU - Cheng, Shuli

AU - Chiang, Chia-Chun

AU - Chiarugi, Alberto

AU - Christensen, Rune Häckert

AU - Chu, Min Kyung

AU - Coppola, Gianluca

AU - Corbelli, Ilenia

AU - Crema, Santiago

AU - De Icco, Roberto

AU - de Tommaso, Marina

AU - Di Lorenzo, Cherubino

AU - Di Stefano, Vincenzo

AU - Diener, Hans-Christoph

AU - Ekizoğlu, Esme

AU - Fallacara, Adriana

AU - Favoni, Valentina

AU - Garces, Kimberly N

AU - Geppetti, Pierangelo

AU - Goicochea, Maria Teresa

AU - Granato, Antonio

AU - Granella, Franco

AU - Guerzoni, Simona

AU - Ha, Woo-Seok

AU - Hassan, Amr

AU - Hirata, Koichi

AU - Hoffmann, Jan

AU - Hüssler, Eva-Maria

AU - Hussein, Mona

AU - Iannone, Luigi Francesco

AU - Jenkins, Bronwyn

AU - Labastida-Ramirez, Alejandro

AU - Laporta, Anna

AU - Levin, Morris

AU - Lupica, Antonino

AU - Mampreso, Edoardo

AU - Martinelli, Daniele

AU - Monteith, Teshamae S

AU - Orologio, Ilaria

AU - Özge, Aynur

AU - Pan, Li-Ling Hope

AU - Panneerchelvam, Lavindren Luke

AU - Peres, Mario F P

AU - Souza, Marcio Nattan Portes

AU - Pozo-Rosich, Patricia

AU - Prudenzano, Maria Pia

AU - Quattrocchi, Silvia

AU - Rainero, Innocenzo

AU - Romanenko, Volodymyr

AU - Romozzi, Marina

AU - Russo, Antonio

AU - Sances, Grazia

AU - Sarchielli, Paola

AU - Schwedt, Todd J

AU - Silvestro, Marcello

AU - Swerts, Diego Belandrino

AU - Tassorelli, Cristina

AU - Tessitore, Alessandro

AU - Togha, Mansoureh

AU - Vaghi, Gloria

AU - Wang, Shuu-Jiun

AU - Ashina, Messoud

AU - Sacco, Simona

PY - 2025

Y1 - 2025

N2 - : We here present evidence-based guidelines for the pharmacological treatment of migraine. These guidelines, created by the Italian Society for the Study of Headache and the International Headache Society, aim to offer clear, actionable recommendations to healthcare professionals. They incorporate evidence-based recommendations from randomized controlled trials and expert-based opinions. The guidelines follow the Grading of Recommendations, Assessment, Development and Evaluation approach for assessing the quality of evidence. The guideline development involved a systematic review of literature across multiple databases, adherence to Cochrane review methods, and a structured framework for data extraction and interpretation. Although the guidelines provide a robust foundation for migraine treatment, they also highlight gaps in current research, such as the paucity of head-to-head drug comparisons and the need for long-term outcome studies. These guidelines serve as a resource to standardize migraine treatment and promote high-quality care across different healthcare settings.

AB - : We here present evidence-based guidelines for the pharmacological treatment of migraine. These guidelines, created by the Italian Society for the Study of Headache and the International Headache Society, aim to offer clear, actionable recommendations to healthcare professionals. They incorporate evidence-based recommendations from randomized controlled trials and expert-based opinions. The guidelines follow the Grading of Recommendations, Assessment, Development and Evaluation approach for assessing the quality of evidence. The guideline development involved a systematic review of literature across multiple databases, adherence to Cochrane review methods, and a structured framework for data extraction and interpretation. Although the guidelines provide a robust foundation for migraine treatment, they also highlight gaps in current research, such as the paucity of head-to-head drug comparisons and the need for long-term outcome studies. These guidelines serve as a resource to standardize migraine treatment and promote high-quality care across different healthcare settings.

KW - acute treatment

KW - drugs

KW - migraine treatment

KW - pharmacological treatments

KW - preventive treatment

KW - acute treatment

KW - drugs

KW - migraine treatment

KW - pharmacological treatments

KW - preventive treatment

UR - https://publicatt.unicatt.it/handle/10807/312874

U2 - 10.1177/03331024241305381

DO - 10.1177/03331024241305381

M3 - Article

SN - 0333-1024

VL - 45

SP - N/A-N/A

JO - Cephalalgia

JF - Cephalalgia

IS - 4

ER -

Evidence-based guidelines for the pharmacological treatment of migraine

Abstract

Keywords

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