TY - JOUR
T1 - Evaluation of two commercial peach extracts for skin prick testing in the diagnosis of hypersensitivity to lipid transfer protein. A multicenter study
AU - Asero, Riccardo
AU - Aruanno, A.
AU - Bresciani, M.
AU - Bresciani, Marco Torkel
AU - Brusca, I.
AU - Carollo, M.
AU - Cecchi, L.
AU - Cortellini, G.
AU - Deleonardi, G.
AU - Farsi, A.
AU - Ferrarini, E.
AU - Gabrielli, G.
AU - Gabrielli, Francesca Augusta
AU - Ingrassia, A.
AU - Mauro, M.
AU - Murzilli, F.
AU - Nucera, Eleonora
AU - Onida, R.
AU - Pastorello, E. A.
AU - Pinter, E.
AU - Rizzi, Angela
AU - Russello, M.
AU - Sacerdoti, C.
AU - Scala, E.
AU - Scala, G.
AU - Villalta, D.
AU - Zampogna, S.
AU - Amato, S.
AU - Mistrello, G.
PY - 2020
Y1 - 2020
N2 - The clinical usefulness of two commercial peach extracts for SPT (by Lofarma SpA and ALK-Abellò, respectively) was compared in a multicenter study carried out in Italy. Peach allergic patients were tested with the two extracts in parallel and underwent the detection of IgE specific for all three peach allergens currently available (Pru p 1, Pru p 3, and Pru p4, respectively). The two extracts were almost identical in terms of sensitivity and specificity, being able to detect virtually all patients sensitized to stable peach allergens (lipid transfer protein [LTP] and, presumably, peamaclein) but scoring negative in patients exclusively sensitive to labile allergens (either PR-10 and/or profilin). Thus, the two extracts represent an excellent tool to carry out a preliminary component-resolved diagnosis of peach allergy at the first patient visit
AB - The clinical usefulness of two commercial peach extracts for SPT (by Lofarma SpA and ALK-Abellò, respectively) was compared in a multicenter study carried out in Italy. Peach allergic patients were tested with the two extracts in parallel and underwent the detection of IgE specific for all three peach allergens currently available (Pru p 1, Pru p 3, and Pru p4, respectively). The two extracts were almost identical in terms of sensitivity and specificity, being able to detect virtually all patients sensitized to stable peach allergens (lipid transfer protein [LTP] and, presumably, peamaclein) but scoring negative in patients exclusively sensitive to labile allergens (either PR-10 and/or profilin). Thus, the two extracts represent an excellent tool to carry out a preliminary component-resolved diagnosis of peach allergy at the first patient visit
KW - SPT
KW - diagnosis
KW - food allergy
KW - lipid transfer protein
KW - peach allergy
KW - SPT
KW - diagnosis
KW - food allergy
KW - lipid transfer protein
KW - peach allergy
UR - http://hdl.handle.net/10807/153686
U2 - 10.23822/EurAnnACI.1764-1489.144
DO - 10.23822/EurAnnACI.1764-1489.144
M3 - Article
SN - 1764-1489
SP - N/A-N/A
JO - European Annals of Allergy and Clinical Immunology
JF - European Annals of Allergy and Clinical Immunology
ER -