Evaluation of stress-related hormones after surgery by laparoscopy or laparotomy

Salvatore Mancuso, Riccardo Marana, Elisabetta Marana, Francesco Meo, Maria Lodovica Maussier, Mario Sciarra, L Muzii, F Paielli

Risultato della ricerca: Contributo in rivistaArticolo in rivista

31 Citazioni (Scopus)

Abstract

Study Objective. To evaluate the stress hormone response after pelvic surgery performed by laparoscopy versus laparotomy. Design. Prospective study. Setting. A tertiary care university hospital. Patients. Ten women were scheduled to undergo laparoscopic surgery and 10 laparotomy for either tubal disease or endometriosis. Interventions. Surgical procedures were performed by laparoscopy or laparotomy for stage III-IV endometriosis, pelvic adhesions, or distal tubal occlusion. The following hormones were measured before the induction of anesthesia in the ward, 60 minutes after the beginning of surgery, at the end of surgery after extubation, and 2 hours and 6 hours after the end of the operation: norepinephrine (NE), epinephrine (E), dopamine (D), adrenocorticotropic hormone (ACTH), cortisol, prolactin (PRL), and GH. Measurement and Main Results. The mean duration of surgery was not significantly different between the two groups. Surgery-related adrenergic activation (E, NE, D) appears more pronounced in the laparotomy group (p < 0.005) during surgery and in the postoperative period. More elevated values for laparotomy were observed also for the other stress hormones (ACTH, cortisol, PRL, GH), even though statistical significance was not always reached. Conclusions. Compared with laparotomy, activation of stress-related factors during laparoscopy seems to be less intense and of shorter duration.
Lingua originaleEnglish
pagine (da-a)229-234
Numero di pagine6
RivistaTHE JOURNAL OF THE AMERICAN ASSOCIATION OF GYNECOLOGIC LAPAROSCOPISTS
Volume3
DOI
Stato di pubblicazionePubblicato - 1996

Keywords

  • Adrenocorticotropic Hormone
  • Adult
  • Biogenic Monoamines
  • Endometriosis
  • Epinephrine
  • Fallopian Tube Diseases
  • Female
  • Growth Hormone
  • Humans
  • Hydrocortisone
  • Laparoscopy
  • Laparotomy
  • Norepinephrine
  • Prolactin
  • Prospective Studies
  • Stress
  • Treatment Outcome
  • article
  • clinical article
  • controlled study
  • corticotropin
  • female
  • growth hormone
  • hormone blood level
  • human
  • hydrocortisone
  • laparoscopic surgery
  • laparotomy
  • postoperative period
  • prolactin, adult
  • stress, Adhesions

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