Estrogens and androgens affect human luteal cell function

Antonio Lanzone, Rosanna Apa, Federica Tiberi, Francesca Romani, Stefania Catino

Risultato della ricerca: Contributo in rivistaArticolo in rivista

9 Citazioni (Scopus)

Abstract

To evaluate estrogens (Es)--E2, estrone (E1), and estriol--and androgens--T and androstendione (A)-effect on P, prostaglandin (PG) F2α, PGE2, and vascular endothelial growth factor (VEGF) release and on VEGF expression in human luteal cells. To elucidate whether androgens effects were direct or mediated by their conversion in Es, an aromatase inhibitor was used. Finally, the luteal effect of the non-aromatizable dihydrotestosterone was evaluated.
Lingua originaleEnglish
pagine (da-a)2257-2263
Numero di pagine7
RivistaFertility and Sterility
Volume94
DOI
Stato di pubblicazionePubblicato - 2010

Keywords

  • Adult
  • Androgens
  • Aromatase Inhibitors
  • Cells, Cultured
  • Dinoprost
  • Drug Evaluation, Preclinical
  • Estrogens
  • Female
  • Humans
  • Luteal Cells
  • Progesterone
  • Testosterone
  • Vascular Endothelial Growth Factor A

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