Estimation of lead-time bias and its impact on the outcome of surveillance for the early diagnosis of hepatocellular carcinoma

Antonio Grieco

Risultato della ricerca: Contributo in rivistaArticolo in rivista

63 Citazioni (Scopus)

Abstract

Lead-time is the time by which diagnosis is anticipated by screening/surveillance with respect to the symptomatic detection of a disease. Any screening program, including surveillance for hepatocellular carcinoma (HCC), is subject to lead-time bias. Data regarding lead-time for HCC are lacking. Aims of the present study were to calculate lead-time and to assess its impact on the benefit obtainable from the surveillance of cirrhotic patients.
Lingua originaleEnglish
pagine (da-a)333-341
Numero di pagine9
RivistaJournal of Hepatology
Volume61
DOI
Stato di pubblicazionePubblicato - 2014

Keywords

  • Cirrhosis
  • Hepatocellular carcinoma
  • Lead-time bias
  • Surveillance

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