TY - JOUR
T1 - Epstein-Barr virus antibodies in serum and cerebrospinal fluid from Multiple Sclerosis, Chronic Inflammatory Demyelinating Polyradiculoneuropathy and Amyotrophic Lateral
AU - Nociti, Viviana
AU - Frisullo, Giovanni
AU - Marti, Alessandro
AU - Luigetti, Marco
AU - Iorio, Raffaele
AU - Patanella, Agata Katia
AU - Bianco, Assunta
AU - Tonali, Pietro Attilio
AU - Grillo, Rita Luciana
AU - Sabatelli, Mario
AU - Batocchi, Anna Paola
PY - 2010
Y1 - 2010
N2 - Elevated anti-Epstein-Barr virus (EBV) antibody levels are present in serum of Multiple sclerosis (MS) patients but literature lacks of studies comparing anti-EBV antibody levels between MS and other neurological diseases. We evaluate anti-VCA IgG and IgM, anti-EBNA1 IgG, anti-Cytomegalovirus IgG and IgM titres in serum and cerebrospinal fluid (CSF) of 267 MS, 50 Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) and 88 Amyotrophic Lateral Sclerosis (ALS) patients. We found increased titres of anti-EBV-IgG in serum and CSF of MS subjects as compared to CIDP and ALS patients thus providing additional evidence for a possible involvement of EBV in MS.
AB - Elevated anti-Epstein-Barr virus (EBV) antibody levels are present in serum of Multiple sclerosis (MS) patients but literature lacks of studies comparing anti-EBV antibody levels between MS and other neurological diseases. We evaluate anti-VCA IgG and IgM, anti-EBNA1 IgG, anti-Cytomegalovirus IgG and IgM titres in serum and cerebrospinal fluid (CSF) of 267 MS, 50 Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) and 88 Amyotrophic Lateral Sclerosis (ALS) patients. We found increased titres of anti-EBV-IgG in serum and CSF of MS subjects as compared to CIDP and ALS patients thus providing additional evidence for a possible involvement of EBV in MS.
KW - anti-EBV antibody
KW - anti-EBV antibody
UR - http://hdl.handle.net/10807/15833
U2 - 10.1016/j.jneuroim.2010.04.007
DO - 10.1016/j.jneuroim.2010.04.007
M3 - Article
SN - 0165-5728
VL - 2010
SP - 149
EP - 152
JO - Journal of Neuroimmunology
JF - Journal of Neuroimmunology
ER -