Epidural infusion of levobupivacaine and sufentanil following thoracotomy

Germano De Cosmo, Elisabetta Congedo, Antonio Mascia, Enrica Adducci, Carlo Lai, Paola Aceto

Risultato della ricerca: Contributo in rivistaArticolo in rivistapeer review

7 Citazioni (Scopus)


A prospective, randomised, double-blind study was conducted to compare the efficacy of two doses of levobupivacaine combined with sufentanil for continuous epidural infusion following thoractomy. A total of 72 patients undergoing lobectomy or pneumonectomy were enrolled. An epidural catheter was inserted between the levels of T4 and T6 before induction of anaesthesia and a loading dose of levobupivacaine and sufentanil was administered. At the end of surgery an epidural infusion was commenced at 5 mlxh(-1) and continued for 48 h. Patients were randomly allocated to receive either levobupivacaine 0.125% (group A) or 0.0625% (group B) and all patients also received sufentanil (1 microgxml(-1)). Visual analogue pain scores after coughing (VASi) were always higher in group B (p < 0.05); VAS pain scores at rest were higher for the first 4 h and at 16 and 28 h in group B (p < 0.05). Total morphine consumption and requests number was lower in group A (p < 0.05). Better pain relief was achieved using epidural 0.125% levobupivacaine.
Lingua originaleEnglish
pagine (da-a)994-999
Numero di pagine6
Stato di pubblicazionePubblicato - 2007


  • epidural analgesia
  • levobupivacaine
  • thoracic surgery


Entra nei temi di ricerca di 'Epidural infusion of levobupivacaine and sufentanil following thoracotomy'. Insieme formano una fingerprint unica.

Cita questo