Ependymoma stem cells are highly sensitive to temozolomide in vitro and in orthotopic models

Daniela Meco; Tiziana Servidei; G Lamorte; E Binda; Vincenzo Arena; Riccardo Riccardi

doi:10.1093/neuonc/nou008

Ependymoma stem cells are highly sensitive to temozolomide in vitro and in orthotopic models

Daniela Meco
, Tiziana Servidei^*
, G Lamorte
, E Binda
, Vincenzo Arena
, Riccardo Riccardi

^*Autore corrispondente per questo lavoro

Risultato della ricerca: Contributo in rivista › Articolo

15 Citazioni (Scopus)

Abstract

Ependymoma management remains challenging because of the inherent chemoresistance of this tumor. To determine whether ependymoma stem cells (SCs) might contribute to therapy resistance, we investigated the sensitivity of ependymoma SCs to temozolomide and etoposide.

Lingua originale	Inglese
pagine (da-a)	N/A-N/A
Rivista	Neuro-Oncology
Numero di pubblicazione	N/A
DOI	https://doi.org/10.1093/neuonc/nou008
Stato di pubblicazione	Pubblicato - 2014

All Science Journal Classification (ASJC) codes

Oncologia
Neurologia (clinica)
Ricerca sul Cancro

Keywords

MGMT
differentiation
ependymoma stem cells
orthotopic models
temozolomide

Accesso al documento

10.1093/neuonc/nou008

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abstract = "Ependymoma management remains challenging because of the inherent chemoresistance of this tumor. To determine whether ependymoma stem cells (SCs) might contribute to therapy resistance, we investigated the sensitivity of ependymoma SCs to temozolomide and etoposide.",

keywords = "MGMT, differentiation, ependymoma stem cells, orthotopic models, temozolomide, MGMT, differentiation, ependymoma stem cells, orthotopic models, temozolomide",

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year = "2014",

doi = "10.1093/neuonc/nou008",

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T1 - Ependymoma stem cells are highly sensitive to temozolomide in vitro and in orthotopic models

AU - Meco, Daniela

AU - Servidei, Tiziana

AU - Lamorte, G

AU - Binda, E

AU - Arena, Vincenzo

AU - Riccardi, Riccardo

PY - 2014

Y1 - 2014

N2 - Ependymoma management remains challenging because of the inherent chemoresistance of this tumor. To determine whether ependymoma stem cells (SCs) might contribute to therapy resistance, we investigated the sensitivity of ependymoma SCs to temozolomide and etoposide.

AB - Ependymoma management remains challenging because of the inherent chemoresistance of this tumor. To determine whether ependymoma stem cells (SCs) might contribute to therapy resistance, we investigated the sensitivity of ependymoma SCs to temozolomide and etoposide.

KW - MGMT

KW - differentiation

KW - ependymoma stem cells

KW - orthotopic models

KW - temozolomide

KW - MGMT

KW - differentiation

KW - ependymoma stem cells

KW - orthotopic models

KW - temozolomide

UR - https://publicatt.unicatt.it/handle/10807/55973

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U2 - 10.1093/neuonc/nou008

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M3 - Article

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SP - N/A-N/A

JO - Neuro-Oncology

JF - Neuro-Oncology

IS - N/A

ER -

Ependymoma stem cells are highly sensitive to temozolomide in vitro and in orthotopic models

Abstract

All Science Journal Classification (ASJC) codes

Keywords

Accesso al documento

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