Endothelial Shear Stress and Coronary Plaque Characteristics in Humans: A Combined Frequency-Domain Optical Coherence Tomography and Computational Fluid Dynamics Study

Luigi Marzio Biasucci, Filippo Crea, Rocco Vergallo, Michail I. Papafaklis, Taishi Yonetsu, Christos V. Bourantas, Ioannis Andreou, Zhao Wang, James G. Fujimoto, Iris Mcnulty, Hang Lee, Charles L. Feldman, Lampros K. Michalis, Peter H. Stone, Ik-Kyung Jang

Risultato della ricerca: Contributo in rivistaArticolo in rivista

61 Citazioni (Scopus)

Abstract

-Despite the exposure of the entire vasculature to the atherogenic effects of systemic risk factors, atherosclerotic plaques preferentially develop at sites with disturbed flow. This study aimed at exploring in vivo the relationship between local endothelial shear stress (ESS) and coronary plaque characteristics in humans, using computational fluid dynamics and frequency-domain optical coherence tomography (FD-OCT).
Lingua originaleEnglish
pagine (da-a)N/A-N/A
RivistaCIRCULATION. CARDIOVASCULAR IMAGING
DOI
Stato di pubblicazionePubblicato - 2014

Keywords

  • atherosclerosis
  • endothelial shear stress
  • optical coherence tomography

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