Endocrine disruptors and human corpus luteum: in vitro effects of phenols on luteal cells function.

Federica Romani; Anna Tropea; Elisa Scarinci; Cinzia Dello Russo; Lucia Lisi; Stefania Catino; Antonio Lanzone; Rosanna Apa

doi:10.1080/10590501.2013.782180

Endocrine disruptors and human corpus luteum: in vitro effects of phenols on luteal cells function.

Federica Romani, Anna Tropea, Elisa Scarinci, Cinzia Dello Russo, Lucia Lisi, Stefania Catino, Antonio Lanzone, Rosanna Apa

IRCCS Oasi Maria SS. - Troina (EN)

Risultato della ricerca: Contributo in rivista › Articolo in rivista

10 Citazioni (Scopus)

Abstract

Endocrine disruptors are well known to impair fertility. The aim of the present study was to investigate the effects of bisphenol A (BPA) and nonylphenol (p-NP) on human luteal function in vitro. In particular, in luteal cells isolated from 21 human corpora lutea progesterone, prostaglandin (PG) F2α, PGE2 and vascular endothelial growth factor (VEGF) release, as well as VEGF expression were evaluated. BPA and p-NP negatively affected both luteal steroidogenesis and luteotrophic/ luteolytic factors balance, without influencing VEGF mRNA expression. Actually, BPA and p-NP impaired human luteal cells function in vitro, underlining the already suggested correlation between phenols and reproductive failure.

Lingua originale	English
pagine (da-a)	170-180
Numero di pagine	11
Rivista	JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH. PART C, ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS
Volume	31
DOI	https://doi.org/10.1080/10590501.2013.782180
Stato di pubblicazione	Pubblicato - 2013

Keywords

bisphenol A
endocrine disruptors
human corpus luteum
luteal function,
nonylphenol

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10.1080/10590501.2013.782180

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Romani, F., Tropea, A., Scarinci, E., Dello Russo, C., Lisi, L., Catino, S., Lanzone, A., & Apa, R. (2013). Endocrine disruptors and human corpus luteum: in vitro effects of phenols on luteal cells function. JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH. PART C, ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS, 31, 170-180. https://doi.org/10.1080/10590501.2013.782180

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title = "Endocrine disruptors and human corpus luteum: in vitro effects of phenols on luteal cells function.",

abstract = "Endocrine disruptors are well known to impair fertility. The aim of the present study was to investigate the effects of bisphenol A (BPA) and nonylphenol (p-NP) on human luteal function in vitro. In particular, in luteal cells isolated from 21 human corpora lutea progesterone, prostaglandin (PG) F2α, PGE2 and vascular endothelial growth factor (VEGF) release, as well as VEGF expression were evaluated. BPA and p-NP negatively affected both luteal steroidogenesis and luteotrophic/ luteolytic factors balance, without influencing VEGF mRNA expression. Actually, BPA and p-NP impaired human luteal cells function in vitro, underlining the already suggested correlation between phenols and reproductive failure.",

keywords = "bisphenol A, endocrine disruptors, human corpus luteum, luteal function,, nonylphenol, bisphenol A, endocrine disruptors, human corpus luteum, luteal function,, nonylphenol",

author = "Federica Romani and Anna Tropea and Elisa Scarinci and {Dello Russo}, Cinzia and Lucia Lisi and Stefania Catino and Antonio Lanzone and Rosanna Apa",

year = "2013",

doi = "10.1080/10590501.2013.782180",

language = "English",

volume = "31",

pages = "170--180",

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publisher = "Marcel Dekker Incorporated:270 Madison Avenue:New York, NY 10016:(800)228-1160, (212)696-9000, EMAIL: [email protected], INTERNET: http://www.dekker.com, Fax: (212)685-4540",

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Romani, F, Tropea, A, Scarinci, E, Dello Russo, C , Lisi, L, Catino, S, Lanzone, A & Apa, R 2013, 'Endocrine disruptors and human corpus luteum: in vitro effects of phenols on luteal cells function.', JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH. PART C, ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS, vol. 31, pagg. 170-180. https://doi.org/10.1080/10590501.2013.782180

Endocrine disruptors and human corpus luteum: in vitro effects of phenols on luteal cells function. / Romani, Federica; Tropea, Anna; Scarinci, Elisa et al.
In: JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH. PART C, ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS, Vol. 31, 2013, pag. 170-180.

Risultato della ricerca: Contributo in rivista › Articolo in rivista

TY - JOUR

T1 - Endocrine disruptors and human corpus luteum: in vitro effects of phenols on luteal cells function.

AU - Romani, Federica

AU - Tropea, Anna

AU - Scarinci, Elisa

AU - Dello Russo, Cinzia

AU - Lisi, Lucia

AU - Catino, Stefania

AU - Lanzone, Antonio

AU - Apa, Rosanna

PY - 2013

Y1 - 2013

N2 - Endocrine disruptors are well known to impair fertility. The aim of the present study was to investigate the effects of bisphenol A (BPA) and nonylphenol (p-NP) on human luteal function in vitro. In particular, in luteal cells isolated from 21 human corpora lutea progesterone, prostaglandin (PG) F2α, PGE2 and vascular endothelial growth factor (VEGF) release, as well as VEGF expression were evaluated. BPA and p-NP negatively affected both luteal steroidogenesis and luteotrophic/ luteolytic factors balance, without influencing VEGF mRNA expression. Actually, BPA and p-NP impaired human luteal cells function in vitro, underlining the already suggested correlation between phenols and reproductive failure.

AB - Endocrine disruptors are well known to impair fertility. The aim of the present study was to investigate the effects of bisphenol A (BPA) and nonylphenol (p-NP) on human luteal function in vitro. In particular, in luteal cells isolated from 21 human corpora lutea progesterone, prostaglandin (PG) F2α, PGE2 and vascular endothelial growth factor (VEGF) release, as well as VEGF expression were evaluated. BPA and p-NP negatively affected both luteal steroidogenesis and luteotrophic/ luteolytic factors balance, without influencing VEGF mRNA expression. Actually, BPA and p-NP impaired human luteal cells function in vitro, underlining the already suggested correlation between phenols and reproductive failure.

KW - bisphenol A

KW - endocrine disruptors

KW - human corpus luteum

KW - luteal function,

KW - nonylphenol

KW - bisphenol A

KW - endocrine disruptors

KW - human corpus luteum

KW - luteal function,

KW - nonylphenol

UR - http://hdl.handle.net/10807/51248

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DO - 10.1080/10590501.2013.782180

M3 - Article

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EP - 180

JO - JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH. PART C, ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS

JF - JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH. PART C, ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS

ER -

Endocrine disruptors and human corpus luteum: in vitro effects of phenols on luteal cells function.

Abstract

Keywords

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