Abstract
From the dualistic classification that divides endometrial cancer (EC) into two types with distinct underlying molecular profiling, histopathology and clinical behavior, arises a deeper understanding of the carcinogenesis pathways. EC treatment comprises different and multimodal therapeutic approaches, such as chemotherapy, radiation therapy or combinations of novel drugs; however, few of these regimens have truly improved progression-free or survival rates in advanced and metastatic settings.
Lingua originale | Inglese |
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pagine (da-a) | 497-509 |
Numero di pagine | 13 |
Rivista | Expert Opinion on Emerging Drugs |
Volume | 19 |
DOI | |
Stato di pubblicazione | Pubblicato - 2014 |
Keywords
- biomarker
- endometrial cancer
- molecular pathway
- target therapy