TY - JOUR
T1 - Embryopathy Following Maternal Biliopancreatic Diversion: Is Bariatric Surgery Really Safe?
AU - Onesimo, Roberta
AU - Proli, Francesco
AU - Leoni, Chiara
AU - Contaldo, Ilaria
AU - Salerni, Annabella
AU - Conti, Giorgio
AU - Tartaglia, Marco
AU - Zampino, Giuseppe
PY - 2020
Y1 - 2020
N2 - Pregnancy after bariatric surgery is usually considered safe. Recently, a few studies reported that bariatric surgery represents a risk factor for birth defects. A case series of six patients, born from women who had undergone biliopancreatic diversion, is reported. The clinical pattern was characterized by psychomotor development delay (100%), microphthalmia (83%), growth retardation (66%), hearing loss (66%), and variable facial dysmorphism. Based on the clinical profile and symptoms reported by women during pregnancy, a causal association between maternal chronic post-surgical malabsorption, congenital anomalies, and neonatal outcome is proposed, with vitamin A deficiency representing a major causing factor. Educational follow-up support, continuous clinical monitoring, and appropriate nutritional assessment appear to be crucial to reduce the potential risk of congenital malformations and child disability.
AB - Pregnancy after bariatric surgery is usually considered safe. Recently, a few studies reported that bariatric surgery represents a risk factor for birth defects. A case series of six patients, born from women who had undergone biliopancreatic diversion, is reported. The clinical pattern was characterized by psychomotor development delay (100%), microphthalmia (83%), growth retardation (66%), hearing loss (66%), and variable facial dysmorphism. Based on the clinical profile and symptoms reported by women during pregnancy, a causal association between maternal chronic post-surgical malabsorption, congenital anomalies, and neonatal outcome is proposed, with vitamin A deficiency representing a major causing factor. Educational follow-up support, continuous clinical monitoring, and appropriate nutritional assessment appear to be crucial to reduce the potential risk of congenital malformations and child disability.
KW - Biliopancreatic diversion
KW - Embryopathy
KW - Nutrition
KW - Obesity surgery safeness
KW - Vitamin A deficiency
KW - Biliopancreatic diversion
KW - Embryopathy
KW - Nutrition
KW - Obesity surgery safeness
KW - Vitamin A deficiency
UR - http://hdl.handle.net/10807/166664
U2 - 10.1007/s11695-020-04882-w
DO - 10.1007/s11695-020-04882-w
M3 - Article
SN - 0960-8923
SP - N/A-N/A
JO - Obesity Surgery
JF - Obesity Surgery
ER -