Eltrombopag before procedures in patients with cirrhosis and thrombocytopenia

Nh Afdhal; Eg Giannini; G Tayyab; A Mohsin; J Lee; A Andriulli; L Jeffers; J Mchutchison; P Chen; K Han; F Campbell; D Hyde; A Brainsky; D Theodore; Antonio Grieco

doi:10.1056/NEJMoa1110709

Eltrombopag before procedures in patients with cirrhosis and thrombocytopenia

Nh Afdhal, Eg Giannini, G Tayyab, A Mohsin, J Lee, A Andriulli, L Jeffers, J Mchutchison, P Chen, K Han, F Campbell, D Hyde, A Brainsky, D Theodore, Antonio Grieco

Università Cattolica del Sacro Cuore

Risultato della ricerca: Contributo in rivista › Articolo in rivista

191 Citazioni (Scopus)

Abstract

Eltrombopag is an oral thrombopoietin-receptor agonist. This study evaluated the efficacy of eltrombopag for increasing platelet counts and reducing the need for platelet transfusions in patients with thrombocytopenia and chronic liver disease who are undergoing an elective invasive procedure.

Lingua originale	English
pagine (da-a)	716-724
Numero di pagine	9
Rivista	THE NEW ENGLAND JOURNAL OF MEDICINE
Volume	367
DOI	https://doi.org/10.1056/NEJMoa1110709
Stato di pubblicazione	Pubblicato - 2012

Keywords

Adolescent
Adult
Aged
Aged, 80 and over
Benzoic Acids
Chronic Disease
Double-Blind Method
Female
Hemorrhage
Humans
Hydrazines
Liver Cirrhosis
Male
Middle Aged
Platelet Count
Platelet Transfusion
Pyrazoles
Receptors, Thrombopoietin
Surgical Procedures, Elective
Thrombocytopenia
Young Adult

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10.1056/NEJMoa1110709

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title = "Eltrombopag before procedures in patients with cirrhosis and thrombocytopenia",

abstract = "Eltrombopag is an oral thrombopoietin-receptor agonist. This study evaluated the efficacy of eltrombopag for increasing platelet counts and reducing the need for platelet transfusions in patients with thrombocytopenia and chronic liver disease who are undergoing an elective invasive procedure.",

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author = "Nh Afdhal and Eg Giannini and G Tayyab and A Mohsin and J Lee and A Andriulli and L Jeffers and J Mchutchison and P Chen and K Han and F Campbell and D Hyde and A Brainsky and D Theodore and Antonio Grieco",

year = "2012",

doi = "10.1056/NEJMoa1110709",

language = "English",

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T1 - Eltrombopag before procedures in patients with cirrhosis and thrombocytopenia

AU - Afdhal, Nh

AU - Giannini, Eg

AU - Tayyab, G

AU - Mohsin, A

AU - Lee, J

AU - Andriulli, A

AU - Jeffers, L

AU - Mchutchison, J

AU - Chen, P

AU - Han, K

AU - Campbell, F

AU - Hyde, D

AU - Brainsky, A

AU - Theodore, D

AU - Grieco, Antonio

PY - 2012

Y1 - 2012

N2 - Eltrombopag is an oral thrombopoietin-receptor agonist. This study evaluated the efficacy of eltrombopag for increasing platelet counts and reducing the need for platelet transfusions in patients with thrombocytopenia and chronic liver disease who are undergoing an elective invasive procedure.

AB - Eltrombopag is an oral thrombopoietin-receptor agonist. This study evaluated the efficacy of eltrombopag for increasing platelet counts and reducing the need for platelet transfusions in patients with thrombocytopenia and chronic liver disease who are undergoing an elective invasive procedure.

KW - Adolescent

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Benzoic Acids

KW - Chronic Disease

KW - Double-Blind Method

KW - Female

KW - Hemorrhage

KW - Humans

KW - Hydrazines

KW - Liver Cirrhosis

KW - Male

KW - Middle Aged

KW - Platelet Count

KW - Platelet Transfusion

KW - Pyrazoles

KW - Receptors, Thrombopoietin

KW - Surgical Procedures, Elective

KW - Thrombocytopenia

KW - Young Adult

KW - Adolescent

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Benzoic Acids

KW - Chronic Disease

KW - Double-Blind Method

KW - Female

KW - Hemorrhage

KW - Humans

KW - Hydrazines

KW - Liver Cirrhosis

KW - Male

KW - Middle Aged

KW - Platelet Count

KW - Platelet Transfusion

KW - Pyrazoles

KW - Receptors, Thrombopoietin

KW - Surgical Procedures, Elective

KW - Thrombocytopenia

KW - Young Adult

UR - http://hdl.handle.net/10807/33915

U2 - 10.1056/NEJMoa1110709

DO - 10.1056/NEJMoa1110709

M3 - Article

SN - 0028-4793

VL - 367

SP - 716

EP - 724

JO - THE NEW ENGLAND JOURNAL OF MEDICINE

JF - THE NEW ENGLAND JOURNAL OF MEDICINE

ER -

Eltrombopag before procedures in patients with cirrhosis and thrombocytopenia

Abstract

Keywords

Accesso al documento

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