MicroRNAs (miRNAs) are intensely studied as candidates for diagnostic and prognostic clinical biomarkers. Faradic impedance spectroscopy (EIS) and differential pulse voltammetry (DPV), coupled to disposable gold electrodes and enzyme amplification of the hybridization event, were used for the development of biosensors for the detection of miRNAs. Biotin-labeled liposomes were employed as nanointerfaces that amplify the primary miRNA-sensing events by their association to the probe–/DNA–miRNA–analyte complex generated onto the transducer.
|Nome||LECTURE NOTES IN ELECTRICAL ENGINEERING|
|Convegno||17th National Conference, Brescia, Italy, 5-7 February 2013|
|Città||BRESCIA -- ITA|
|Periodo||5/2/13 → 7/2/13|
- Chronic Lymphocytic Leukemia Differential Pulse Voltammetry Electrochemical Signal Electron Transfer Resistance miRNA Detection