Efficacy of combined surgery and antifungal therapies for the management of invasive zygomycoses in patients with haematological malignancies

Cg Valentini; A Candoni; Luana Fianchi; Brunella Posteraro; E Simeone; Fabrizio Costa; Maurizio Sanguinetti; Mt Voso; Morena Caira; R Fanin; Livio Pagano

doi:10.1111/j.1439-0507.2008.01672.x

Efficacy of combined surgery and antifungal therapies for the management of invasive zygomycoses in patients with haematological malignancies

Cg Valentini^*, A Candoni, Luana Fianchi, Brunella Posteraro, E Simeone, Fabrizio Costa, Maurizio Sanguinetti, Mt Voso, Morena Caira, R Fanin, Livio Pagano

^*Autore corrispondente per questo lavoro

Risultato della ricerca: Contributo in rivista › Articolo

8 Citazioni (Scopus)

Abstract

We report two cases of invasive zygomycoses occurring in severely immunocompromised patients with haematological malignancies that were successfully treated with liposomal amphotericin B and surgical debridement, followed by oral administration of posaconazole. These cases demonstrated that an early instituted, aggressive and combined therapeutic approach results in a recovery from invasive fungal infection, without any relapse of infection, thanks to secondary prophylaxis using posaconazole.

Lingua originale	Inglese
pagine (da-a)	89-92
Numero di pagine	4
Rivista	Mycoses
Volume	53
Numero di pubblicazione	1
DOI	https://doi.org/10.1111/j.1439-0507.2008.01672.x
Stato di pubblicazione	Pubblicato - 2010

All Science Journal Classification (ASJC) codes

Dermatologia
Malattie Infettive

Keywords

Aged
Amphotericin B
Antifungal Agents
Hematologic Neoplasms
Humans
Immunocompromised Host
Male
Middle Aged
Treatment Outcome
Triazoles
Zygomycosis

Accesso al documento

10.1111/j.1439-0507.2008.01672.x

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abstract = "We report two cases of invasive zygomycoses occurring in severely immunocompromised patients with haematological malignancies that were successfully treated with liposomal amphotericin B and surgical debridement, followed by oral administration of posaconazole. These cases demonstrated that an early instituted, aggressive and combined therapeutic approach results in a recovery from invasive fungal infection, without any relapse of infection, thanks to secondary prophylaxis using posaconazole.",

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AU - Valentini, Cg

AU - Candoni, A

AU - Fianchi, Luana

AU - Posteraro, Brunella

AU - Simeone, E

AU - Costa, Fabrizio

AU - Sanguinetti, Maurizio

AU - Voso, Mt

AU - Caira, Morena

AU - Fanin, R

AU - Pagano, Livio

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KW - Treatment Outcome

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Efficacy of combined surgery and antifungal therapies for the management of invasive zygomycoses in patients with haematological malignancies

Abstract

All Science Journal Classification (ASJC) codes

Keywords

Accesso al documento

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