Efficacy of combined surgery and antifungal therapies for the management of invasive zygomycoses in patients with haematological malignancies

Brunella Posteraro, Maurizio Sanguinetti, Livio Pagano, Luana Fianchi, Morena Caira, Cg Valentini, A Candoni, E Simeone, Fabrizio Costa, Mt Voso, R Fanin

Risultato della ricerca: Contributo in rivistaArticolo in rivista

8 Citazioni (Scopus)

Abstract

We report two cases of invasive zygomycoses occurring in severely immunocompromised patients with haematological malignancies that were successfully treated with liposomal amphotericin B and surgical debridement, followed by oral administration of posaconazole. These cases demonstrated that an early instituted, aggressive and combined therapeutic approach results in a recovery from invasive fungal infection, without any relapse of infection, thanks to secondary prophylaxis using posaconazole.
Lingua originaleEnglish
pagine (da-a)89-92
Numero di pagine4
RivistaMycoses
Volume53
DOI
Stato di pubblicazionePubblicato - 2010

Keywords

  • Aged
  • Amphotericin B
  • Antifungal Agents
  • Hematologic Neoplasms
  • Humans
  • Immunocompromised Host
  • Male
  • Middle Aged
  • Treatment Outcome
  • Triazoles
  • Zygomycosis

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