Effect of smoking one cigarette on antioxidant metabolites in the saliva of healthy smokers

Silvia Persichilli, Alvaro Mordente, Bruno Zappacosta, Pasquale De Sole, Bruno Giardina

Risultato della ricerca: Contributo in rivistaArticolo in rivista

86 Citazioni (Scopus)

Abstract

Concentrations of glutathione, uric acid and total antioxidant activity, expressed as Trolox (a water-soluble vitamin E analogue) equivalent, were measured in the saliva of healthy non-smokers and smokers before and just after smoking a single cigarette. There was no statistically significant difference between smokers and non-smokers in uric acid concentrations and total radical-trapping antioxidant capacity, but glutathione concentrations were significantly (p < 0.05) higher in smokers. Smoking of a single cigarette induced a significant reduction in glutathione concentration (p < 0.05). Salivary antioxidant power may affect individual sensitivity toward tobacco stress.
Lingua originaleEnglish
pagine (da-a)485-488
Numero di pagine4
RivistaArchives of Oral Biology
Volume44
Stato di pubblicazionePubblicato - 1999

Keywords

  • Adult
  • Antioxidants
  • Benzothiazoles
  • Chromatography, High Pressure Liquid
  • Female
  • Free Radical Scavengers
  • Glutathione
  • Humans
  • Indicators and Reagents
  • Male
  • Middle Aged
  • Peroxidase
  • Saliva
  • Smoking
  • Sulfonic Acids
  • Uric Acid

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