Effect of oral sebacic Acid on postprandial glycemia, insulinemia, and glucose rate of appearance in type 2 diabetes

Geltrude Mingrone, Amerigo Iaconelli, Angela Maria Rita Favuzzi, Amalia Gastaldelli, Christophe Binnert, Katherine Macé

Risultato della ricerca: Contributo in rivistaArticolo in rivista

10 Citazioni (Scopus)

Abstract

Dicarboxylic acids are natural products with the potential of being an alternate dietary source of energy. We aimed to evaluate the effect of sebacic acid (a 10-carbon dicarboxylic acid; C10) ingestion on postprandial glycemia and glucose rate of appearance (Ra) in healthy and type 2 diabetic subjects. Furthermore, the effect of C10 on insulin-mediated glucose uptake and on GLUT4 expression was assessed in L6 muscle cells in vitro.
Lingua originaleEnglish
pagine (da-a)2327-2332
Numero di pagine6
RivistaDiabetes Care
Volume33
DOI
Stato di pubblicazionePubblicato - 2010

Keywords

  • Absorptiometry, Photon
  • Animals
  • Biological Transport
  • Blood Glucose
  • Blotting, Western
  • Body Composition
  • C-Peptide
  • Cell Line
  • Decanoic Acids
  • Diabetes Mellitus, Type 2
  • Dicarboxylic Acids
  • Female
  • Gas Chromatography-Mass Spectrometry
  • Humans
  • Immunoprecipitation
  • Insulin
  • Male
  • Middle Aged
  • Postprandial Period
  • Rats

Fingerprint

Entra nei temi di ricerca di 'Effect of oral sebacic Acid on postprandial glycemia, insulinemia, and glucose rate of appearance in type 2 diabetes'. Insieme formano una fingerprint unica.

Cita questo