Efavirenz associated with cognitive disorders in otherwise asymptomatic HIV-infected patients

Nicoletta Ciccarelli; Massimiliano Fabbiani; Simona Di Giambenedetto; Iuri Fanti; Eleonora Baldonero; Laura Bracciale; Enrica Tamburrini; Roberto Cauda; Andrea De Luca; Maria Caterina Silveri

doi:10.1212/WNL.0b013e31821670fb

Efavirenz associated with cognitive disorders in otherwise asymptomatic HIV-infected patients

Nicoletta Ciccarelli, Massimiliano Fabbiani, Simona Di Giambenedetto, Iuri Fanti, Eleonora Baldonero, Laura Bracciale, Enrica Tamburrini, Roberto Cauda, Andrea De Luca, Maria Caterina Silveri

Risultato della ricerca: Contributo in rivista › Articolo in rivista

Abstract

Despite the availability of potent antiretroviral regimens (combination antiretroviral therapy [cART]), HIV-associated neurocognitive disorders (HAND) are increasingly recognized. Our aim was to investigate the prevalence and treatment-related correlates of HAND, exploring the potential neurotoxicity of antiretrovirals on cognitive functions.

Lingua originale	English
pagine (da-a)	1403-1409
Numero di pagine	7
Rivista	Neurology
Volume	76
DOI	https://doi.org/10.1212/WNL.0b013e31821670fb
Stato di pubblicazione	Pubblicato - 2011

Keywords

Activities of Daily Living
Adult
Anti-HIV Agents
Antiretroviral Therapy, Highly Active
Benzoxazines
Case-Control Studies
Chi-Square Distribution
Cognition Disorders
Cohort Studies
Female
HIV Infections
Humans
Male
Mental Status Schedule
Middle Aged
Neuropsychological Tests
Retrospective Studies
Young Adult

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title = "Efavirenz associated with cognitive disorders in otherwise asymptomatic HIV-infected patients",

abstract = "Despite the availability of potent antiretroviral regimens (combination antiretroviral therapy [cART]), HIV-associated neurocognitive disorders (HAND) are increasingly recognized. Our aim was to investigate the prevalence and treatment-related correlates of HAND, exploring the potential neurotoxicity of antiretrovirals on cognitive functions.",

keywords = "Activities of Daily Living, Adult, Anti-HIV Agents, Antiretroviral Therapy, Highly Active, Benzoxazines, Case-Control Studies, Chi-Square Distribution, Cognition Disorders, Cohort Studies, Female, HIV Infections, Humans, Male, Mental Status Schedule, Middle Aged, Neuropsychological Tests, Retrospective Studies, Young Adult, Activities of Daily Living, Adult, Anti-HIV Agents, Antiretroviral Therapy, Highly Active, Benzoxazines, Case-Control Studies, Chi-Square Distribution, Cognition Disorders, Cohort Studies, Female, HIV Infections, Humans, Male, Mental Status Schedule, Middle Aged, Neuropsychological Tests, Retrospective Studies, Young Adult",

author = "Nicoletta Ciccarelli and Massimiliano Fabbiani and {Di Giambenedetto}, Simona and Iuri Fanti and Eleonora Baldonero and Laura Bracciale and Enrica Tamburrini and Roberto Cauda and {De Luca}, Andrea and Silveri, {Maria Caterina}",

year = "2011",

doi = "10.1212/WNL.0b013e31821670fb",

language = "English",

volume = "76",

pages = "1403--1409",

journal = "Neurology",

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T1 - Efavirenz associated with cognitive disorders in otherwise asymptomatic HIV-infected patients

AU - Ciccarelli, Nicoletta

AU - Fabbiani, Massimiliano

AU - Di Giambenedetto, Simona

AU - Fanti, Iuri

AU - Baldonero, Eleonora

AU - Bracciale, Laura

AU - Tamburrini, Enrica

AU - Cauda, Roberto

AU - De Luca, Andrea

AU - Silveri, Maria Caterina

PY - 2011

Y1 - 2011

N2 - Despite the availability of potent antiretroviral regimens (combination antiretroviral therapy [cART]), HIV-associated neurocognitive disorders (HAND) are increasingly recognized. Our aim was to investigate the prevalence and treatment-related correlates of HAND, exploring the potential neurotoxicity of antiretrovirals on cognitive functions.

AB - Despite the availability of potent antiretroviral regimens (combination antiretroviral therapy [cART]), HIV-associated neurocognitive disorders (HAND) are increasingly recognized. Our aim was to investigate the prevalence and treatment-related correlates of HAND, exploring the potential neurotoxicity of antiretrovirals on cognitive functions.

KW - Activities of Daily Living

KW - Adult

KW - Anti-HIV Agents

KW - Antiretroviral Therapy, Highly Active

KW - Benzoxazines

KW - Case-Control Studies

KW - Chi-Square Distribution

KW - Cognition Disorders

KW - Cohort Studies

KW - Female

KW - HIV Infections

KW - Humans

KW - Male

KW - Mental Status Schedule

KW - Middle Aged

KW - Neuropsychological Tests

KW - Retrospective Studies

KW - Young Adult

KW - Activities of Daily Living

KW - Adult

KW - Anti-HIV Agents

KW - Antiretroviral Therapy, Highly Active

KW - Benzoxazines

KW - Case-Control Studies

KW - Chi-Square Distribution

KW - Cognition Disorders

KW - Cohort Studies

KW - Female

KW - HIV Infections

KW - Humans

KW - Male

KW - Mental Status Schedule

KW - Middle Aged

KW - Neuropsychological Tests

KW - Retrospective Studies

KW - Young Adult

UR - http://hdl.handle.net/10807/25031

U2 - 10.1212/WNL.0b013e31821670fb

DO - 10.1212/WNL.0b013e31821670fb

M3 - Article

SN - 0028-3878

VL - 76

SP - 1403

EP - 1409

JO - Neurology

JF - Neurology

ER -

Efavirenz associated with cognitive disorders in otherwise asymptomatic HIV-infected patients

Abstract

Keywords

OSS delle Nazioni Unite

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