TY - JOUR
T1 - Early feed restriction programs metabolic disorders in fattening merino lambs
AU - Frutos, Javier
AU - Andrés, Sonia
AU - Trevisi, Erminio
AU - Yáñez-Ruiz, David R.
AU - López, Secundino
AU - Santos, Alba
AU - Giráldez, Francisco Javier
PY - 2018
Y1 - 2018
N2 - Early postnatal nutrition may have a significant subsequent impact on metabolic disorders during the entire lifespan of lambs. The aim of the present study was to describe the changes in biochemical, immunological, hepatic, and ruminal parameters of fattening lambs derived from early feed restriction during the suckling phase. Twenty-four merino lambs (average body weight, BW, 4.81 ± 0.256 kg) were used, 12 of them were milk-fed ad libitum (ADL) remaining permanently with their dams, whereas the other 12 lambs (restricted, RES) were subjected to milk restriction. After weaning, all the lambs were fed 35 g/kg BW per day of the same complete pelleted diet to ensure no differences between groups in dry matter intake (603 vs. 607 g/day for ADL and RES lambs, respectively, p = 0.703), and were slaughtered at a BW of 27 kg. Biochemical profiles revealed higher concentrations of ceruloplasmin and low-density lipoproteins, whereas insulin concentration was lower in the RES lambs compared to the ADL group. Liver thiobarbituric acid reactive substances were lower in the RES lambs. No significant differences in ruminal or blood immunological parameters were found. In conclusion, early feed restriction promoted metabolic disorders not related to ruminal acidosis occurrence, which can compromise the health status during the fattening period of merino lambs.
AB - Early postnatal nutrition may have a significant subsequent impact on metabolic disorders during the entire lifespan of lambs. The aim of the present study was to describe the changes in biochemical, immunological, hepatic, and ruminal parameters of fattening lambs derived from early feed restriction during the suckling phase. Twenty-four merino lambs (average body weight, BW, 4.81 ± 0.256 kg) were used, 12 of them were milk-fed ad libitum (ADL) remaining permanently with their dams, whereas the other 12 lambs (restricted, RES) were subjected to milk restriction. After weaning, all the lambs were fed 35 g/kg BW per day of the same complete pelleted diet to ensure no differences between groups in dry matter intake (603 vs. 607 g/day for ADL and RES lambs, respectively, p = 0.703), and were slaughtered at a BW of 27 kg. Biochemical profiles revealed higher concentrations of ceruloplasmin and low-density lipoproteins, whereas insulin concentration was lower in the RES lambs compared to the ADL group. Liver thiobarbituric acid reactive substances were lower in the RES lambs. No significant differences in ruminal or blood immunological parameters were found. In conclusion, early feed restriction promoted metabolic disorders not related to ruminal acidosis occurrence, which can compromise the health status during the fattening period of merino lambs.
KW - Animal Science and Zoology
KW - Feed efficiency
KW - Inflammation
KW - Metabolic syndrome
KW - Microbiota
KW - Nutritional programming
KW - Ruminal acidosis
KW - Veterinary (all)
KW - Animal Science and Zoology
KW - Feed efficiency
KW - Inflammation
KW - Metabolic syndrome
KW - Microbiota
KW - Nutritional programming
KW - Ruminal acidosis
KW - Veterinary (all)
UR - http://hdl.handle.net/10807/126997
UR - http://www.mdpi.com/2076-2615/8/6/83/pdf
U2 - 10.3390/ani8060083
DO - 10.3390/ani8060083
M3 - Article
SN - 2076-2615
VL - 8
SP - N/A-N/A
JO - Animals
JF - Animals
ER -